Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Pathway Overview

Name .....................................................	:	Glycolysis / gluconeogenesis
Related pathway (?) The pathway found in other databases to which this pathway is related. .....................................................	:	ERROR
Number of reactions .....................................................	:	19
In WormPaths (?) If the pathway is available as a WormPaths map you will find the name and link of map here. .....................................................	:	Glycolysis / gluconeogenesis

External links

Reactions (?) Click to see these reactions in the related KEGG pathway (only enzymes that are represented in kegg are highlighted).

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01602Name: D-Glucose 1-epimerase Type: Regular Location: Cytosol KEGG ID: R01602 click to see details on this item	5.1.3.3Name: aldose 1-epimerase Other names: mutarotase, aldose mutarotase, galactose mutarotase, galactose 1-epimerase, D-galactose 1-epimerase click to see details on this item	[c] : glc-D-AName: alpha-D-Glucose Formula: C6H12O6 Charge: 0 click to see details on this item		glc-D-BName: beta-D-Glucose Formula: C6H12O6 Charge: 0 click to see details on this item	C01B4.6 | Y19D10A.16	Glycolysis / gluconeogenesis
RC01070Name: beta-D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming) Type: Regular Location: Cytosol KEGG ID: R01070 click to see details on this item	4.1.2.13Name: fructose-bisphosphate aldolase Other names: aldolase, fructose-1,6-bisphosphate triosephosphate-lyase, fructose diphosphate aldolase, diphosphofructose aldolase, fructose 1,6-diphosphate aldolase, ketose 1-phosphate aldolase, phosphofructoaldolase, zymohexase, fructoaldolase, fructose 1-phosphate aldolase, fructose 1-monophosphate aldolase, 1,6-Diphosphofructose aldolase, SMALDO, D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase click to see details on this item	[c] : fdpName: "D-Fructose 1,6-bisphosphate" Formula: C6H10O12P2 Charge: -4 click to see details on this item		dhapName: Dihydroxyacetone phosphate Formula: C3H5O6P Charge: -2 click to see details on this item + g3pName: Glyceraldehyde 3-phosphate Formula: C3H5O6P Charge: -2 click to see details on this item	aldo-2 | aldo-1	Glycolysis / gluconeogenesis
RC04780Name: beta-D-Fructose 1,6-bisphosphate 1-phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R04780 click to see details on this item	3.1.3.11Name: fructose-bisphosphatase Other names: hexose diphosphatase, FBPase, fructose 1,6-diphosphatase, fructose 1,6-diphosphate phosphatase, D-fructose 1,6-diphosphatase, fructose 1,6-bisphosphatase, fructose diphosphatase, fructose diphosphate phosphatase, fructose bisphosphate phosphatase, fructose 1,6-bisphosphate 1-phosphatase, fructose 1,6-bisphosphate phosphatase, hexose bisphosphatase, D-fructose-1,6-bisphosphate phosphatase click to see details on this item	[c] : fdpName: "D-Fructose 1,6-bisphosphate" Formula: C6H10O12P2 Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		f6pName: D-Fructose 6-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	fbp-1	Glycolysis / gluconeogenesis
RC04779Name: ATP:D-fructose-6-phosphate 1-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R04779 click to see details on this item	2.7.1.11Name: 6-phosphofructokinase Other names: phosphohexokinase, phosphofructokinase I, phosphofructokinase (phosphorylating), 6-phosphofructose 1-kinase, ATP-dependent phosphofructokinase, D-fructose-6-phosphate 1-phosphotransferase, fructose 6-phosphate kinase, fructose 6-phosphokinase, nucleotide triphosphate-dependent phosphofructokinase, phospho-1,6-fructokinase, PFK click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + f6pName: D-Fructose 6-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + fdpName: "D-Fructose 1,6-bisphosphate" Formula: C6H10O12P2 Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	pfk-1.2 | pfk-1.1	Glycolysis / gluconeogenesis
RC01015Name: D-glyceraldehyde-3-phosphate aldose-ketose-isomerase Type: Regular Location: Cytosol KEGG ID: R01015 click to see details on this item	5.3.1.1Name: triose-phosphate isomerase Other names: phosphotriose isomerase, triose phosphoisomerase, triose phosphate mutase, D-glyceraldehyde-3-phosphate ketol-isomerase click to see details on this item	[c] : g3pName: Glyceraldehyde 3-phosphate Formula: C3H5O6P Charge: -2 click to see details on this item		dhapName: Dihydroxyacetone phosphate Formula: C3H5O6P Charge: -2 click to see details on this item	tpi-1	Glycolysis / gluconeogenesis
RC01061Name: D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating) Type: Regular Location: Cytosol KEGG ID: R01061 click to see details on this item	1.2.1.12Name: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Other names: triosephosphate dehydrogenase, dehydrogenase, glyceraldehyde phosphate, phosphoglyceraldehyde dehydrogenase, 3-phosphoglyceraldehyde dehydrogenase, NAD+-dependent glyceraldehyde phosphate dehydrogenase, glyceraldehyde phosphate dehydrogenase (NAD+), glyceraldehyde-3-phosphate dehydrogenase (NAD+), NADH-glyceraldehyde phosphate dehydrogenase, glyceraldehyde-3-P-dehydrogenase click to see details on this item	[c] : g3pName: Glyceraldehyde 3-phosphate Formula: C3H5O6P Charge: -2 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		13dpgName: 3-Phospho-D-glyceroyl phosphate Formula: C3H4O10P2 Charge: -4 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	gpd-4 | gpd-3 | gpd-2 | gpd-1	Glycolysis / gluconeogenesis
RC01512Name: ATP:3-phospho-D-glycerate 1-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01512 click to see details on this item	2.7.2.3Name: phosphoglycerate kinase Other names: PGK, 3-PGK, ATP-3-phospho-D-glycerate-1-phosphotransferase, ATP:D-3-phosphoglycerate 1-phosphotransferase, 3-phosphoglycerate kinase, 3-phosphoglycerate phosphokinase, 3-phosphoglyceric acid kinase, 3-phosphoglyceric acid phosphokinase, 3-phosphoglyceric kinase, glycerate 3-phosphate kinase, glycerophosphate kinase, phosphoglyceric acid kinase, phosphoglyceric kinase, phosphoglycerokinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + 3pgName: 3-Phospho-D-glycerate Formula: C3H4O7P Charge: -3 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + 13dpgName: 3-Phospho-D-glyceroyl phosphate Formula: C3H4O10P2 Charge: -4 click to see details on this item	pgk-1	Glycolysis / gluconeogenesis
RC01518Name: 2-Phospho-D-glycerate 2,3-phosphomutase Type: Regular Location: Cytosol KEGG ID: R01518 click to see details on this item	5.4.2.12Name: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) Other names: cofactor independent phosphoglycerate mutase, 2,3-diphosphoglycerate-independent phosphoglycerate mutase, phosphoglycerate phosphomutase (ambiguous), phosphoglyceromutase (ambiguous), monophosphoglycerate mutase (ambiguous), monophosphoglyceromutase (ambiguous), GriP mutase (ambiguous), PGA mutase (ambiguous), iPGM, iPGAM, PGAM-i click to see details on this item	[c] : 2pgName: D-Glycerate 2-phosphate Formula: C3H4O7P Charge: -3 click to see details on this item		3pgName: 3-Phospho-D-glycerate Formula: C3H4O7P Charge: -3 click to see details on this item	ipgm-1	Glycolysis / gluconeogenesis
RC00658Name: 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming) Type: Regular Location: Cytosol KEGG ID: R00658 click to see details on this item	4.2.1.11Name: phosphopyruvate hydratase Other names: enolase, 2-phosphoglycerate dehydratase, 14-3-2-protein, nervous-system specific enolase, phosphoenolpyruvate hydratase, 2-phosphoglycerate dehydratase, 2-phosphoglyceric dehydratase, 2-phosphoglycerate enolase, gamma-enolase, 2-phospho-D-glycerate hydro-lyase click to see details on this item	[c] : 2pgName: D-Glycerate 2-phosphate Formula: C3H4O7P Charge: -3 click to see details on this item		pepName: Phosphoenolpyruvate Formula: C3H2O6P Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	enol-1	Glycolysis / gluconeogenesis
RC00431Name: GTP:oxaloacetate carboxy-lyase (adding GTP, phosphoenolpyruvate-forming) Type: Regular Location: Cytosol KEGG ID: R00431 click to see details on this item	4.1.1.32Name: phosphoenolpyruvate carboxykinase (GTP) Other names: phosphoenolpyruvate carboxylase, phosphopyruvate carboxylase, phosphopyruvate (guanosine triphosphate) carboxykinase, phosphoenolpyruvic carboxykinase (GTP), phosphopyruvate carboxylase (GTP), phosphoenolpyruvic carboxylase (GTP), phosphoenolpyruvic carboxykinase, phosphoenolpyruvate carboxykinase, PEP carboxylase, GTP:oxaloacetate carboxy-lyase (transphosphorylating) click to see details on this item	[c] : gtpName: GTP Formula: C10H12N5O14P3 Charge: -4 click to see details on this item + oaaName: Oxaloacetate Formula: C4H2O5 Charge: -2 click to see details on this item		gdpName: GDP Formula: C10H12N5O11P2 Charge: -3 click to see details on this item + pepName: Phosphoenolpyruvate Formula: C3H2O6P Charge: -3 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	pck-1 | pck-2 | pck-3	Glycolysis / gluconeogenesis
RC00200Name: ATP:pyruvate 2-O-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00200 click to see details on this item	2.7.1.40Name: pyruvate kinase Other names: phosphoenolpyruvate kinase, phosphoenol transphosphorylase click to see details on this item	[c] : adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + pepName: Phosphoenolpyruvate Formula: C3H2O6P Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item	pyk-1 | pyk-2	Glycolysis / gluconeogenesis
RM00209Name: pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating) Type: Regular Location: Mitochondria KEGG ID: R00209 click to see details on this item	1.2.4.1Name: pyruvate dehydrogenase (acetyl-transferring) Other names: MtPDC (mitochondrial pyruvate dehydogenase complex), pyruvate decarboxylase, pyruvate dehydrogenase, pyruvate dehydrogenase (lipoamide), pyruvate dehydrogenase complex, pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating), pyruvic acid dehydrogenase, pyruvic dehydrogenase click to see details on this item 1.8.1.4Name: dihydrolipoyl dehydrogenase Other names: LDP-Glc, LDP-Val, dehydrolipoate dehydrogenase, diaphorase, dihydrolipoamide dehydrogenase, dihydrolipoamide:NAD+ oxidoreductase, dihydrolipoic dehydrogenase, dihydrothioctic dehydrogenase, lipoamide dehydrogenase (NADH), lipoamide oxidoreductase (NADH), lipoamide reductase, lipoamide reductase (NADH), lipoate dehydrogenase, lipoic acid dehydrogenase, lipoyl dehydrogenase, protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase click to see details on this item 2.3.1.12Name: dihydrolipoyllysine-residue acetyltransferase Other names: acetyl-CoA:dihydrolipoamide S-acetyltransferase, dihydrolipoamide S-acetyltransferase, dihydrolipoate acetyltransferase, dihydrolipoic transacetylase, dihydrolipoyl acetyltransferase, lipoate acetyltransferase, lipoate transacetylase, lipoic acetyltransferase, lipoic acid acetyltransferase, lipoic transacetylase, lipoylacetyltransferase, thioltransacetylase A, transacetylase X, enzyme-dihydrolipoyllysine:acetyl-CoA S-acetyltransferase, acetyl-CoA:enzyme 6-N-(dihydrolipoyl)lysine S-acetyltransferase click to see details on this item	[m] : pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	(pdha-1 & pdhb-1) & (dlat-2 | dlat-1) & dld-1	Glycolysis / gluconeogenesis
RC00703Name: (S)-Lactate:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00703 click to see details on this item	1.1.1.27Name: L-lactate dehydrogenase Other names: lactic acid dehydrogenase, L(+)-nLDH, L-(+)-lactate dehydrogenase, L-lactic dehydrogenase, L-lactic acid dehydrogenase, lactate dehydrogenase, lactate dehydrogenase NAD+-dependent, lactic dehydrogenase, NAD+-lactate dehydrogenase click to see details on this item	[c] : lac-LName: L-Lactate Formula: C3H5O3 Charge: -1 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	ldh-1	Glycolysis / gluconeogenesis
RC00711Name: Acetaldehyde:NADP+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00711 click to see details on this item	1.2.1.5Name: aldehyde dehydrogenase [NAD(P)+] Other names: ALDH click to see details on this item	[c] : acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	alh-5	Glycolysis / gluconeogenesis
RC00710Name: Acetaldehyde:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00710 click to see details on this item	1.2.1.3Name: aldehyde dehydrogenase (NAD+) Other names: CoA-independent aldehyde dehydrogenase, m-methylbenzaldehyde dehydrogenase, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, propionaldehyde dehydrogenase, aldehyde dehydrogenase (NAD) click to see details on this item	[c] : acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	(alh-2 | alh-4) | (alh-11 | alh-12)	Glycolysis / gluconeogenesis
RM00710Name: Acetaldehyde:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R00710 click to see details on this item	1.2.1.3Name: aldehyde dehydrogenase (NAD+) Other names: CoA-independent aldehyde dehydrogenase, m-methylbenzaldehyde dehydrogenase, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, propionaldehyde dehydrogenase, aldehyde dehydrogenase (NAD) click to see details on this item	[m] : acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	(alh-1 | alh-2 | alh-4) | alh-9	Glycolysis / gluconeogenesis
RC00754Name: ethanol:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00754 click to see details on this item	1.1.1.1Name: alcohol dehydrogenase Other names: aldehyde reductase, ADH, alcohol dehydrogenase (NAD), aliphatic alcohol dehydrogenase, ethanol dehydrogenase, NAD-dependent alcohol dehydrogenase, NAD-specific aromatic alcohol dehydrogenase, NADH-alcohol dehydrogenase, NADH-aldehyde dehydrogenase, primary alcohol dehydrogenase, yeast alcohol dehydrogenase click to see details on this item	[c] : etohName: Ethanol Formula: C2H6O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	H24K24.3 | (D2063.1 | sodh-1 | sodh-2)	Glycolysis / gluconeogenesis
RC00235Name: Acetate:CoA ligase (AMP-forming) Type: Regular Location: Cytosol KEGG ID: R00235 click to see details on this item	6.2.1.1Name: acetate---CoA ligase Other names: acetyl-CoA synthetase, acetyl activating enzyme, acetate thiokinase, acyl-activating enzyme, acetyl coenzyme A synthetase, acetic thiokinase, acetyl CoA ligase, acetyl CoA synthase, acetyl-coenzyme A synthase, short chain fatty acyl-CoA synthetase, short-chain acyl-coenzyme A synthetase, ACS click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item		ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item + accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item	acs-19	Glycolysis / gluconeogenesis
RM00711Name: Acetaldehyde:NADP+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R00711 click to see details on this item	1.2.1.5Name: aldehyde dehydrogenase [NAD(P)+] Other names: ALDH click to see details on this item	[m] : acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	alh-5	Glycolysis / gluconeogenesis

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