WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	acald
Name .....................................................	:	Acetaldehyde, etc.Ethanal
Model ID .....................................................	:	C00084
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00084
Formula .....................................................	:	C2H4O
Charge .....................................................	:	0
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	acald
Other associations .....................................................	:	See reaction table below (14 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Go to map

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01410Name: cyanide conversion to alpha-Aminopropiononitrile Type: Regular Location: Cytosol KEGG ID: R01410 click to see details on this item	Unknown	[c] : cyanName: Hydrogen cyanide Formula: CHN Charge: 0 click to see details on this item + acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item		apropName: alpha-Aminopropiononitrile Formula: C3H7N2 Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	Unknown	Miscellaneous
RC00748Name: ethanolamine-phosphate phosphate-lyase (deaminating) (acetaldehyde-forming) Type: Regular Location: Cytosol KEGG ID: R00748 click to see details on this item	4.2.3.2Name: ethanolamine-phosphate phospho-lyase Other names: O-phosphoethanolamine-phospholyase, amino alcohol O-phosphate phospholyase, O-phosphorylethanol-amine phospho-lyase, ethanolamine-phosphate phospho-lyase (deaminating) click to see details on this item	[c] : ethampName: Ethanolamine phosphate Formula: C2H7NO4P Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	T01B11.2	Glycerophospholipid metabolism
RC00751Name: L-threonine acetaldehyde-lyase (glycine-forming) Type: Regular Location: Cytosol KEGG ID: R00751 click to see details on this item	4.1.2.5Name: L-threonine aldolase Other names: L-threonine acetaldehyde-lyase click to see details on this item	[c] : thr-LName: L-Threonine Formula: C4H9NO3 Charge: 0 click to see details on this item		acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + glyName: Glycine Formula: C2H5NO2 Charge: 0 click to see details on this item	R102.4	Glycine and threonine metabolism
RC06171Name: L-Allothreonine acetaldehyde-lyase Type: Regular Location: Cytosol KEGG ID: R06171 click to see details on this item	4.1.2.5Name: L-threonine aldolase Other names: L-threonine acetaldehyde-lyase click to see details on this item	[c] : athr-LName: L-Allo-threonine Formula: C4H9NO3 Charge: 0 click to see details on this item		acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + glyName: Glycine Formula: C2H5NO2 Charge: 0 click to see details on this item	R102.4	Glycine and threonine metabolism
RM00751Name: L-threonine acetaldehyde-lyase (glycine-forming) Type: Regular Location: Mitochondria KEGG ID: R00751 click to see details on this item	4.1.2.5Name: L-threonine aldolase Other names: L-threonine acetaldehyde-lyase click to see details on this item	[m] : thr-LName: L-Threonine Formula: C4H9NO3 Charge: 0 click to see details on this item		acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + glyName: Glycine Formula: C2H5NO2 Charge: 0 click to see details on this item	R102.4	Glycine and threonine metabolism
RC00711Name: Acetaldehyde:NADP+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00711 click to see details on this item	1.2.1.5Name: aldehyde dehydrogenase [NAD(P)+] Other names: ALDH click to see details on this item	[c] : acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	alh-5	Glycolysis / gluconeogenesis
RC00710Name: Acetaldehyde:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00710 click to see details on this item	1.2.1.3Name: aldehyde dehydrogenase (NAD+) Other names: CoA-independent aldehyde dehydrogenase, m-methylbenzaldehyde dehydrogenase, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, propionaldehyde dehydrogenase, aldehyde dehydrogenase (NAD) click to see details on this item	[c] : acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	(alh-2 \| alh-4) \| (alh-11 \| alh-12)	Glycolysis / gluconeogenesis
RM00710Name: Acetaldehyde:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R00710 click to see details on this item	1.2.1.3Name: aldehyde dehydrogenase (NAD+) Other names: CoA-independent aldehyde dehydrogenase, m-methylbenzaldehyde dehydrogenase, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, propionaldehyde dehydrogenase, aldehyde dehydrogenase (NAD) click to see details on this item	[m] : acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	(alh-1 \| alh-2 \| alh-4) \| alh-9	Glycolysis / gluconeogenesis
RC00754Name: ethanol:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00754 click to see details on this item	1.1.1.1Name: alcohol dehydrogenase Other names: aldehyde reductase, ADH, alcohol dehydrogenase (NAD), aliphatic alcohol dehydrogenase, ethanol dehydrogenase, NAD-dependent alcohol dehydrogenase, NAD-specific aromatic alcohol dehydrogenase, NADH-alcohol dehydrogenase, NADH-aldehyde dehydrogenase, primary alcohol dehydrogenase, yeast alcohol dehydrogenase click to see details on this item	[c] : etohName: Ethanol Formula: C2H6O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	H24K24.3 \| (D2063.1 \| sodh-1 \| sodh-2)	Glycolysis / gluconeogenesis
RM00711Name: Acetaldehyde:NADP+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R00711 click to see details on this item	1.2.1.5Name: aldehyde dehydrogenase [NAD(P)+] Other names: ALDH click to see details on this item	[m] : acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	alh-5	Glycolysis / gluconeogenesis
RC01066Name: 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming) Type: Regular Location: Cytosol KEGG ID: R01066 click to see details on this item	4.1.2.4Name: deoxyribose-phosphate aldolase Other names: phosphodeoxyriboaldolase, deoxyriboaldolase, deoxyribose-5-phosphate aldolase, 2-deoxyribose-5-phosphate aldolase, 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase click to see details on this item	[c] : 2dr5pName: 2-Deoxy-D-ribose 5-phosphate Formula: C5H9O7P Charge: -2 click to see details on this item		g3pName: Glyceraldehyde 3-phosphate Formula: C3H5O6P Charge: -2 click to see details on this item + acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item	F09E5.3	Pentose phosphate pathway
TCE1302Name: Acetaldehyde transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item[e]		acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item[c]	Not determined	Transport
TCM0073Name: Acetaldehyde transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item[m]		acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item[c]	Not determined	Transport
EX00084Name: Acetaldehyde exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	acaldName: Acetaldehyde Formula: C2H4O Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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