Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	dttp
Name .....................................................	:	dTTP, etc.Deoxythymidine triphosphate, Deoxythymidine 5'-triphosphate, TTP
Model ID .....................................................	:	C00459
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00459
Formula .....................................................	:	C10H13N2O14P3
Charge .....................................................	:	-4
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	dttp
Other associations .....................................................	:	See reaction table below (11 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Pyrimidine metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC02093Name: ATP:dTDP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R02093 click to see details on this item	2.7.4.6Name: nucleoside-diphosphate kinase Other names: nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphokinase, nucleotide phosphate kinase, UDP kinase, uridine diphosphate kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + dtdpName: dTDP Formula: C10H13N2O11P2 Charge: -3 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item	R05G6.5 | Y48G8AL.15 | ndk-1	Pyrimidine metabolism
BIO0004Name: DNA synthesis Type: Biomass Location: Cytosol KEGG ID: R00379 click to see details on this item	2.7.7.7Name: DNA-directed DNA polymerase Other names: DNA polymerase I, DNA polymerase II, DNA polymerase III, DNA polymerase alpha, DNA polymerase beta, DNA polymerase gamma, DNA nucleotidyltransferase (DNA-directed), DNA nucleotidyltransferase (DNA-directed), deoxyribonucleate nucleotidyltransferase, deoxynucleate polymerase, deoxyribonucleic acid duplicase, deoxyribonucleic acid polymerase, deoxyribonucleic duplicase, deoxyribonucleic polymerase, deoxyribonucleic polymerase I, DNA duplicase, DNA nucleotidyltransferase, DNA polymerase, DNA replicase, DNA-dependent DNA polymerase, duplicase, Klenow fragment, sequenase, Taq DNA polymerase, Taq Pol I, Tca DNA polymerase click to see details on this item	[c] : (0.325) datpName: dATP Formula: C10H12N5O12P3 Charge: -4 click to see details on this item + (0.175) dctpName: dCTP Formula: C9H12N3O13P3 Charge: -4 click to see details on this item + (0.175) dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + (0.325) dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item + (0.368) atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + (0.368) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		DNAName: DNA (biomass) Formula: X Charge: 0 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item + (0.368) adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + (0.368) piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + (0.368) hName: H+ Formula: H Charge: 1 click to see details on this item	Y47D3A.29 & pole-1 & pole-2 & F10C2.4 & K04C2.2 & polg-1 & (polq-1 | helq-1) & Y37B11A.2 & Y53F4B.3 & polh-1 & polk-1 & T26A5.8 & div-1 & F12F6.7 & (pri-1 | T24C4.5) & pri-2 & R04F11.3	Biomass assembly
TCM0092Name: dTTP and ADP transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[m] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[c]		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[c] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0116Name: dTTP and dGDP transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	dgdpName: dGDP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[m] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[c]		dgdpName: dGDP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[c] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCE1157Name: dTTP transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[e]		dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[c]	Not determined	Transport
TCM0153Name: dTTP and dCDP transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	dcdpName: dCDP Formula: C9H12N3O10P2 Charge: -3 click to see details on this item[m] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[c]		dcdpName: dCDP Formula: C9H12N3O10P2 Charge: -3 click to see details on this item[c] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0080Name: dTTP and ATP transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[m] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[c]		atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0160Name: dTDP and dTTP transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	dtdpName: dTDP Formula: C10H13N2O11P2 Charge: -3 click to see details on this item[m] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[c]		dtdpName: dTDP Formula: C10H13N2O11P2 Charge: -3 click to see details on this item[c] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0167Name: dTTP and dADP transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	dadpName: dADP Formula: C10H12N5O9P2 Charge: -3 click to see details on this item[m] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[c]		dadpName: dADP Formula: C10H12N5O9P2 Charge: -3 click to see details on this item[c] + dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0131Name: dTTP and dUDP transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[c] + dudpName: dUDP Formula: C9H11N2O11P2 Charge: -3 click to see details on this item[m]		dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[m] + dudpName: dUDP Formula: C9H11N2O11P2 Charge: -3 click to see details on this item[c]	Not determined	Transport
EX00459Name: dTTP exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item[e]			Not applicable	Exchange with the environment

The information and tools provided in this website are to be used for academic purposes only.