Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	dgtp
Name .....................................................	:	dGTP, etc.2'-Deoxyguanosine 5'-triphosphate, Deoxyguanosine 5'-triphosphate, Deoxyguanosine triphosphate
Model ID .....................................................	:	C00286
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00286
Formula .....................................................	:	C10H12N5O13P3
Charge .....................................................	:	-4
Localization .....................................................	:	Mitochondria, Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	dgtp
Other associations .....................................................	:	See reaction table below (10 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Purine metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01855Name: 2-Deoxyguanosine 5-triphosphate diphosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01855 click to see details on this item	3.6.1.19Name: nucleoside-triphosphate diphosphatase Other names: nucleoside-triphosphate pyrophosphatase click to see details on this item	[c] : dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		dgmpName: dGMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	hap-1	Purine metabolism
RC01857Name: ATP:dGDP phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01857 click to see details on this item	2.7.4.6Name: nucleoside-diphosphate kinase Other names: nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphokinase, nucleotide phosphate kinase, UDP kinase, uridine diphosphate kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + dgdpName: dGDP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item	R05G6.5 | Y48G8AL.15 | ndk-1	Purine metabolism
BIO0004Name: DNA synthesis Type: Biomass Location: Cytosol KEGG ID: R00379 click to see details on this item	2.7.7.7Name: DNA-directed DNA polymerase Other names: DNA polymerase I, DNA polymerase II, DNA polymerase III, DNA polymerase alpha, DNA polymerase beta, DNA polymerase gamma, DNA nucleotidyltransferase (DNA-directed), DNA nucleotidyltransferase (DNA-directed), deoxyribonucleate nucleotidyltransferase, deoxynucleate polymerase, deoxyribonucleic acid duplicase, deoxyribonucleic acid polymerase, deoxyribonucleic duplicase, deoxyribonucleic polymerase, deoxyribonucleic polymerase I, DNA duplicase, DNA nucleotidyltransferase, DNA polymerase, DNA replicase, DNA-dependent DNA polymerase, duplicase, Klenow fragment, sequenase, Taq DNA polymerase, Taq Pol I, Tca DNA polymerase click to see details on this item	[c] : (0.325) datpName: dATP Formula: C10H12N5O12P3 Charge: -4 click to see details on this item + (0.175) dctpName: dCTP Formula: C9H12N3O13P3 Charge: -4 click to see details on this item + (0.175) dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + (0.325) dttpName: dTTP Formula: C10H13N2O14P3 Charge: -4 click to see details on this item + (0.368) atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + (0.368) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		DNAName: DNA (biomass) Formula: X Charge: 0 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item + (0.368) adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + (0.368) piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item + (0.368) hName: H+ Formula: H Charge: 1 click to see details on this item	Y47D3A.29 & pole-1 & pole-2 & F10C2.4 & K04C2.2 & polg-1 & (polq-1 | helq-1) & Y37B11A.2 & Y53F4B.3 & polh-1 & polk-1 & T26A5.8 & div-1 & F12F6.7 & (pri-1 | T24C4.5) & pri-2 & R04F11.3	Biomass assembly
TCM0143Name: dGTP and ATP transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[m] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c]		atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0098Name: dGDP and dGTP transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	dgdpName: dGDP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[m] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c]		dgdpName: dGDP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[c] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0096Name: dGTP and ADP transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[m] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c]		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[c] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0200Name: dUDP and dGTP transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c] + dudpName: dUDP Formula: C9H11N2O11P2 Charge: -3 click to see details on this item[m]		dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[m] + dudpName: dUDP Formula: C9H11N2O11P2 Charge: -3 click to see details on this item[c]	Not determined	Transport
TCM0204Name: dGTP and dADP transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	dadpName: dADP Formula: C10H12N5O9P2 Charge: -3 click to see details on this item[m] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c]		dadpName: dADP Formula: C10H12N5O9P2 Charge: -3 click to see details on this item[c] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0127Name: dGTP and dCDP transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	dcdpName: dCDP Formula: C9H12N3O10P2 Charge: -3 click to see details on this item[m] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c]		dcdpName: dCDP Formula: C9H12N3O10P2 Charge: -3 click to see details on this item[c] + dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[m]	Not determined	Transport
TCM0070Name: dTDP and dGTP transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c] + dtdpName: dTDP Formula: C10H13N2O11P2 Charge: -3 click to see details on this item[m]		dgtpName: dGTP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[m] + dtdpName: dTDP Formula: C10H13N2O11P2 Charge: -3 click to see details on this item[c]	Not determined	Transport

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