Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	taur
Name .....................................................	:	Taurine, etc.2-Aminoethanesulfonic acid, Aminoethylsulfonic acid
Model ID .....................................................	:	C00245
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00245
Formula .....................................................	:	C2H7NO3S
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	taur
Other associations .....................................................	:	See reaction table below (6 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Biosynthesis of bile acid-like molecules (c), Taurine and hypotaurine metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC03720Name: Choloyl-CoA:taurine N-choloyltransferase Type: Regular Location: Cytosol KEGG ID: R03720 click to see details on this item	2.3.1.65Name: bile acid-CoA:amino acid N-acyltransferase Other names: glycine---taurine N-acyltransferase, amino acid N-choloyltransferase, BAT, glycine N-choloyltransferase, BACAT, cholyl-CoA glycine-taurine N-acyltransferase, cholyl-CoA:taurine N-acyltransferase click to see details on this item	[c] : cholcoaName: Choloyl-CoA Formula: C45H70N7O20P3S Charge: -4 click to see details on this item + taurName: Taurine Formula: C2H7NO3S Charge: 0 click to see details on this item		coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + tcholaName: taurocholic acid Formula: C26H45NO7S Charge: 0 click to see details on this item	C31H5.6 | W03D8.8 | T05E7.1 | K05B2.4	Biosynthesis of bile acid-like molecules
RC01682Name: 3-Sulfo-L-alanine carboxy-lyase (taurine-forming) Type: Regular Location: Cytosol KEGG ID: R01682 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[c] : LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + taurName: Taurine Formula: C2H7NO3S Charge: 0 click to see details on this item	unc-25	Taurine and hypotaurine metabolism
RC01687Name: (5-L-glutamyl)-peptide:taurine 5-glutamyltransferase Type: Regular Location: Cytosol KEGG ID: R01687 click to see details on this item	2.3.2.2Name: gamma-glutamyltransferase Other names: glutamyl transpeptidase, alpha-glutamyl transpeptidase, gamma-glutamyl peptidyltransferase, gamma-glutamyl transpeptidase (ambiguous), gamma-GPT, gamma-GT, gamma-GTP, L-gamma-glutamyl transpeptidase, L-gamma-glutamyltransferase, L-glutamyltransferase, GGT (ambiguous), gamma-glutamyltranspeptidase (ambiguous) click to see details on this item	[c] : taurName: Taurine Formula: C2H7NO3S Charge: 0 click to see details on this item + gthrdName: Reduced glutathione Formula: C10H16N3O6S Charge: -1 click to see details on this item		cglyName: Cys-Gly Formula: C5H10N2O3S Charge: 0 click to see details on this item + glutaurName: 5-L-Glutamyl-taurine Formula: C7H13N2O6S Charge: -1 click to see details on this item	C53D5.5 | H14N18.4 | T03D8.6 | T19H12.6 | Y7A9A.1 | Y97E10AR.2	Taurine and hypotaurine metabolism
RC01681Name: Hypotaurine oxidase Type: Regular Location: Cytosol KEGG ID: R01681 click to see details on this item	1.8.1.3Name: hypotaurine dehydrogenase click to see details on this item	[c] : (2) hName: H+ Formula: H Charge: 1 click to see details on this item + (2) hyptaurName: Hypotaurine Formula: C2H6NO2S Charge: -1 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		(2) taurName: Taurine Formula: C2H7NO3S Charge: 0 click to see details on this item	Unknown	Taurine and hypotaurine metabolism
TCE0417Name: Taurine and Sodium transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	(2.0) na1Name: Sodium Formula: Na Charge: 1 click to see details on this item[e] + taurName: Taurine Formula: C2H7NO3S Charge: 0 click to see details on this item[e]		(2.0) na1Name: Sodium Formula: Na Charge: 1 click to see details on this item[c] + taurName: Taurine Formula: C2H7NO3S Charge: 0 click to see details on this item[c]	Not determined	Transport
EX00245Name: Taurine exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	taurName: Taurine Formula: C2H7NO3S Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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