Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	Lcyst
Name .....................................................	:	L-Cysteate, etc.L-Cysteic acid, 3-Sulfoalanine, 2-Amino-3-sulfopropionic acid
Model ID .....................................................	:	C00506
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00506
Formula .....................................................	:	C3H6NO5S
Charge .....................................................	:	-1
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	Lcyst
Other associations .....................................................	:	See reaction table below (6 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Cysteine metabolism (c,m), Taurine and hypotaurine metabolism (c,m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM02433Name: L-cysteate:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R02433 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item	[m] : LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item + akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item		3spyrName: 3-Sulfopyruvate Formula: C3H2O6S Charge: -2 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-2.1 | got-2.2	Cysteine metabolism
RC01682Name: 3-Sulfo-L-alanine carboxy-lyase (taurine-forming) Type: Regular Location: Cytosol KEGG ID: R01682 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[c] : LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + taurName: Taurine Formula: C2H7NO3S Charge: 0 click to see details on this item	unc-25	Taurine and hypotaurine metabolism
RCC0074Name: sulfinic acid oxidation Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	spontaneous	[c] : 3salaName: 3-Sulfino-L-alanine Formula: C3H5NO4S Charge: -2 click to see details on this item + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	Not applicable	Cysteine metabolism
RMC0074Name: sulfinic acid oxidation Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	spontaneous	[m] : 3salaName: 3-Sulfino-L-alanine Formula: C3H5NO4S Charge: -2 click to see details on this item + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	Not applicable	Cysteine metabolism
TCE5338Name: L-Cysteate transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	clName: Chloride Formula: Cl Charge: -1 click to see details on this item[e] + LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item[e] + (2.0) na1Name: Sodium Formula: Na Charge: 1 click to see details on this item[e]		clName: Chloride Formula: Cl Charge: -1 click to see details on this item[c] + LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item[c] + (2.0) na1Name: Sodium Formula: Na Charge: 1 click to see details on this item[c]	Not determined	Transport
EX00506Name: L-Cysteate exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	LcystName: L-Cysteate Formula: C3H6NO5S Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

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