WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	so3
Name .....................................................	:	Sulfite, etc.Sulfurous acid
Model ID .....................................................	:	C00094
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00094
Formula .....................................................	:	O3S
Charge .....................................................	:	-2
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	so3
Other associations .....................................................	:	See reaction table below (13 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Cysteine metabolism (c,m), Sulfur metabolism (c,m)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0009Name: 3-sulfinopyruvate hydrolase Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	spontaneous	[c] : 3snpyrName: 3-Sulfinopyruvate Formula: C3H2O5S Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item	Not applicable	Cysteine metabolism
RMC0009Name: 3-sulfinopyruvate hydrolase Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	spontaneous	[m] : 3snpyrName: 3-Sulfinopyruvate Formula: C3H2O5S Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item	Not applicable	Cysteine metabolism
RC03105Name: 3-Mercaptopyruvate:cyanide sulfurtransferase Type: Regular Location: Cytosol KEGG ID: R03105 click to see details on this item	2.8.1.2Name: 3-mercaptopyruvate sulfurtransferase Other names: beta-mercaptopyruvate sulfurtransferase click to see details on this item	[c] : mercppyrName: Mercaptopyruvate Formula: C3H3O3S Charge: -1 click to see details on this item + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item		tsulName: Thiosulfate Formula: O3S2 Charge: -2 click to see details on this item + pyrName: Pyruvate Formula: C3H3O3 Charge: -1 click to see details on this item	mpst-1 \| mpst-2 \| mpst-3 \| mpst-4 \| mpst-5 \| mpst-6 \| mpst-7	Cysteine metabolism
RM01931Name: thiosulfate:cyanide sulfurtranserase Type: Regular Location: Mitochondria KEGG ID: R01931 click to see details on this item	2.8.1.1Name: thiosulfate sulfurtransferase Other names: thiosulfate cyanide transsulfurase, thiosulfate thiotransferase, rhodanese, rhodanase click to see details on this item	[m] : cyanName: Hydrogen cyanide Formula: CHN Charge: 0 click to see details on this item + tsulName: Thiosulfate Formula: O3S2 Charge: -2 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item + tcyntName: Thiocyanate Formula: CNS Charge: -1 click to see details on this item	mpst-1 \| mpst-2 \| mpst-3 \| mpst-4 \| mpst-5 \| mpst-6 \| mpst-7	Sulfur metabolism
RC01931Name: thiosulfate:cyanide sulfurtranserase Type: Regular Location: Cytosol KEGG ID: R01931 click to see details on this item	2.8.1.1Name: thiosulfate sulfurtransferase Other names: thiosulfate cyanide transsulfurase, thiosulfate thiotransferase, rhodanese, rhodanase click to see details on this item	[c] : cyanName: Hydrogen cyanide Formula: CHN Charge: 0 click to see details on this item + tsulName: Thiosulfate Formula: O3S2 Charge: -2 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item + tcyntName: Thiocyanate Formula: CNS Charge: -1 click to see details on this item	mpst-1 \| mpst-2 \| mpst-3 \| mpst-4 \| mpst-5 \| mpst-6 \| mpst-7	Sulfur metabolism
RMC0054Name: Sulfite:ferricytochrome-c oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	1.8.3.1Name: sulfite oxidase click to see details on this item	(2.0) ficytCName: Ferricytochrome c Formula: C42H42FeN8O8S2R4 Charge: 1 click to see details on this item[m] + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item[c] + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item[c]		(2.0) focytCName: Ferrocytochrome C Formula: C42H42FeN8O8S2R4 Charge: 0 click to see details on this item[m] + (2.0) hName: H+ Formula: H Charge: 1 click to see details on this item[c] + so4Name: Sulfate Formula: O4S Charge: -2 click to see details on this item[c]	suox-1 & (cyc-2.1 \| cyc-2.2)	Sulfur metabolism
RM00781Name: sulfur dioxygenase Type: Regular Location: Mitochondria KEGG ID: R00781 click to see details on this item	1.13.11.18Name: sulfur dioxygenase Other names: sulfur oxygenase, sulfur:oxygen oxidoreductase click to see details on this item	[m] : sName: Sulfur Formula: S Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	ethe-1	Sulfur metabolism
RM01875Name: Thiosulfate:thiol sulfurtransferase Type: Regular Location: Mitochondria KEGG ID: R01875 click to see details on this item	2.8.1.3Name: thiosulfate---thiol sulfurtransferase Other names: glutathione-dependent thiosulfate reductase, sulfane reductase, sulfane sulfurtransferase click to see details on this item	[m] : so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item + h2sName: Hydrogen sulfide Formula: H2S Charge: 0 click to see details on this item + gthoxName: Oxidized glutathione Formula: C20H30N6O12S2 Charge: -2 click to see details on this item		tsulName: Thiosulfate Formula: O3S2 Charge: -2 click to see details on this item + (2) gthrdName: Reduced glutathione Formula: C10H16N3O6S Charge: -1 click to see details on this item	Unknown	Sulfur metabolism
RM00533Name: Sulfite:oxygen oxidoreductase Type: Regular Location: Cytosol, Mitochondria KEGG ID: R00533 click to see details on this item	1.8.3.1Name: sulfite oxidase click to see details on this item	so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item[c] + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item[m] + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item[c]		so4Name: Sulfate Formula: O4S Charge: -2 click to see details on this item[c] + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item[m]	suox-1	Sulfur metabolism
TCE5369Name: Sulfite transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	na1Name: Sodium Formula: Na Charge: 1 click to see details on this item[c] + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item[c]		na1Name: Sodium Formula: Na Charge: 1 click to see details on this item[e] + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item[e]	Not determined	Transport
TCM0217Name: Sulfite and L-Malate transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	mal-LName: L-Malate Formula: C4H4O5 Charge: -2 click to see details on this item[c] + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item[m]		mal-LName: L-Malate Formula: C4H4O5 Charge: -2 click to see details on this item[m] + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item[c]	Not determined	Transport
TCM0139Name: Sulfite and Fumarate transport Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	fumName: Fumarate Formula: C4H2O4 Charge: -2 click to see details on this item[c] + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item[m]		fumName: Fumarate Formula: C4H2O4 Charge: -2 click to see details on this item[m] + so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item[c]	Not determined	Transport
EX00094Name: Sulfite exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	so3Name: Sulfite Formula: O3S Charge: -2 click to see details on this item[e]			Not applicable	Exchange with the environment

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