WormFlux: mechanistic analysis of C. elegans metabolism

Gene Overview

Name .....................................................	:	hpo-8
Sequence ID .....................................................	:	T15B7.2
Status (?) Can be one of the following two: Curated (manually annotated or based on a curated SACURE result), or Not curated (SACURE result reported without manual check). .....................................................	:	Curated
KO (?) The KEGG orthology group (KO) that is associated with this gene. .....................................................	:	K10703PHS1 PAS2; very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase [EC:4.2.1.134]
Enzymes in the model (?) Enzymes that are part of the current metabolic network model. .....................................................	:	4.2.1.134names: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase;PHS1 (gene name);PAS2 (gene name)
Other enzymes (?) Enzymes that are associated with this gene in the WormFlux database, but not included in the current network model. .....................................................	:	None
Model reactions (?) Reactions that are part of the current metabolic network model. See the bottom of this page for a table of reactions. .....................................................	:	RCC0064, RCC0063, RCC0124, RCC0210, RCC0072, RCC0073, RC07760, RCC0070
Relevant model reactions (?) Model reactions that follow from the KEGG reactions associated with this gene, but that exclude this gene due to differences in reaction specificity or localization compared to the predictions for this gene. .....................................................	:	ERROR
Other reactions (?) KEGG reactions that are associated with this gene in the WormFlux database, but not included in the current network model. .....................................................	:	None

In WormPaths (?) Pathway maps where this gene is represented are listed here. .....................................................	:	Ascaroside biosynthesis, Fatty acid biosynthesis

External links

WBGene00020517

CELE_T15B7.2

O17040

► | Gene-KO-Enzyme-Reaction Associations (click to view)▼ | Gene-KO-Enzyme-Reaction Associations (click to hide)

SACURE (?) Associations established by SACURE (Systematic Annotation by CUration and REgression).

SACURE pipeline annotates genes based on a logistic function that converts evidence from multiple resources into a KEGG orthology decision, which is then associated with enzymes and reactions. False positives and false negatives of the logistic function are separated out during manual curation for making exceptional decisions.

See HELP in the upper menu for a description of the SACURE pipeline.

See below for a summary of association scores from SACURE.

Results (?) KO: Associated KEGG Orthology groups
Enzyme: Associated enzymes in EC numbering
Reactions: Associated reactions from KEGG reaction database.

Confidence level is indicated for each association as a function of overall SACURE score (a probability of true association; see below in the SACURE scores section). Score ranges for HIGH, MEDIUM, and LOW confidence levels are >0.99, 0.90-0.99, and 0.50-0.90, respectively. If an association is accepted with a probability less than 0.50 (due to an exceptional reason), then the confidence level is LOW.

Not determined indicates that annotation analysis resulted in no clear associations.

	ID - Confidence
KO	K10703 - High
Enzyme	4.2.1.134 - High
Reaction	R07760 - High R02685 - High R10827 - High

Comments

Based on the logistic function.
See scores from predictors and the logistic function below (SACURE summary).

Reconstruction (?) Associations established during the reconstruction process by lenient annotation, literature search, or gap-filling.

Results (?) KO: Associated KEGG Orthology groups
Enzyme: Associated enzymes in EC numbering
Reactions: Associated reactions from KEGG reaction database or custom reactions developed during reconstruction.

	ID - Confidence
KO	K10703 - High
Enzyme	4.2.1.134 - High
Reaction	RCC0210 - Medium

Comments

Based on the logistic function.
Specific enzyme and reaction associations were made during ascaroside biosynthesis reconstruction (see note #37).

► | SACURE Summary (click to view)▼ | SACURE scores (click to hide)

Score table (?) Association scores for KOs best matching to the query gene according to each annotation predictor, and for the accepted KO if there is any (rightmost columns).

The predictors are ordered in decreasing weight of contribution to the decision-making process in SACURE.

See above for the final decision on the annotation of this gene.

Predictor	Best scoring KOs	Best score	K10703	K10703
KEGG (?) Score represents the annotation in KEGG database by June 2014. Takes a value of either 0 (KO is not associated with the query gene) or 1 (KO is associated with the query gene).	K10703	1	1	1
Cluster (?) Score represents the degree of relatedness of a KO to the query gene based on the clustering in the phylogenetic tree of protein sequences (see below for the tree). Takes values from 0 to 1.	K10703	1.00	1.00	1.00
myKEGG (?) Score represents the degree of relatedness of a KO to the query gene based on the Smith-Waterman alignment of protein sequence with most similar sequences from all organisms in the KEGG database. Takes values from 0 to 1. KOunknown indicates the score for sequences without any KO association in KEGG database.	K10703	1.00	1.00	1.00
Tree (?) Score shows the degree of relatedness of a KO to the query gene based on the density of this KO in the phylogenetic tree of protein sequences (see below for the tree). Takes values from 0 to 2 as the score is normalized to the second best KO. KOunknown indicates the score for sequences without any KO association in KEGG database.	K10703	2.00	2.00	2.00
KOG (?) Score indicates the absence or presence of a KO in association with one of the orthologs of the query gene according to a eukaryotic orthology database independent of KEGG (see HELP* in the upper menu for details). Takes a value of either 0 (absent) or 1 (present*).	Not applicable	0	0	0
WormBase (?) Score represents matching between the KEGG descriptions of a KO (KO name and all related enzyme names) and the descriptions of the query gene in WormBase (gene overview and protein domains). Value is increased by 0.5 for every perfect word match and reduced by 0.1 for each character interruption. A non-matching word always creates a 0 score. WormBase description used for this gene was: "Protein tyrosine phosphatase-like protein, PTPLA $ Protein-tyrosine phosphatase-like, PTPLA $$ Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase hpo-8"	K11240 K01110 and 36 more...All best scoring KOs: K11240, K01110, K16723, K06778, K05866, K05867, K06777, K06776, K14165, K14167, K07817, K06639, K16662, K07293, K16667, K05698, K02555, K05693, K17619, K05695, K01104, K05697, K05694, K05696, K17622, K17621, K16910, K17620, K06478, K06645, K08114, K02078, K15616, K13297, K14819, K04458, K04459, K14394	1.5	0.0	0.0
Overall (?) Overall score from SACURE that represents the logistic-regression-based probability of acceptance of a KO in association with the query gene.	K10703	1.000	1.000	1.000

► | Localization scores (click to view)▼ | Localization scores (click to hide)

Score table (?) Localization scores for proteins encoded by the query gene.

Each predictor is used to determine whether the protein is localized to mitochondria or other compartment.

Together with other genes and other predictors, these scores were used in the determination of the subcellular location of reactions associated with the query gene (see below for the reactions).

Predictor	Mitochondrial	Other
Mitoprot (?) Score represents the predicted probability that the protein is targeted to mitochondria (mitochondrial score) or not (other score) according to Mitoprot (click to reach). If multiple isofoms of the same protein are available the highest scores are shown for each compartment.	0.78	0.22
MitoMiner (?) Score evaluates the evidence for mitochondrial targeting based on the orthologs in 12 eukaryotic model organisms that are in the MitoMiner database (click to reach). If clear orthologs for the query gene are available in MitoMiner organisms, the score takes a value between 0 and 1 as a function of the ratio of orthologs that have hits (contributes to the mitochondrial score) or no hits (determines the other score) in the database. Mitochondrial score is also a function of the strength of the evidence for the orthologs found in the database (experimental evidence is given a higher weight than theoretical evidence during scoring).	0.00	1.00
UniProt (?) Score shows the subcellular localization of proteins encoded by this gene as reported in UniProt (click to reach) in October 2014. If a report is available, the score takes a value of either 0 (not reported to be localized to the pertaining compartment) or 1 (reported to be localized to the pertaining compartment).	Not available	Not available
Org. DB (?) Score shows the subcellular localization of proteins encoded by this gene as reported in Organelle Database (click to reach). If a report is available, the score takes a value of either 0 (not reported to be localized to the pertaining compartment) or 1 (reported to be localized to the pertaining compartment).	Not available	Not available

► | Phylogenetic tree (click to view)▼ | Phylogenetic tree (click to hide)

(?) Phylogenetic tree of protein sequences including the query gene, nearest matches in selected organisms from different taxonomic groups, and paralogs in C. elegans. All sequences are obtained from KEGG database.

This figure is interactive, click items to reach relevant KEGG pages.

A low number of orthologs represented on this tree indicates the lack of similar sequences in other organisms.

See below for the legend.

Sequence labels indicate KO, taxonomy or model organism, organism name (if taxonomic group), and gene name, respectively. CEL, C. elegans; HSA, H. sapiens; DME, D. melanogaster; ATH, A. thaliana; SCE, S. cerevisiae; BAC, bacteria; ARC, archaea; PRO, protists; FUN, fungi; PLA, plants; INV, invertebrates; NEM, nematodes; ART, arthropods; VER, vertebrates; MAM, mammals. Parenthetical information for organisms other than CEL indicates whether the genes are introduced as best matches (B) or reciprocal best hits (R) to the query gene. Parenthetical information for CEL indicates whether the genes are introduced as paralogues (P) of the query gene or as reciprocal best matches to one of the other organisms in the tree (B). Organism abbreviations are from KEGG.

Reactions

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0064Name: long chain fatty acid elongation (Linolenoyl-CoA to Eicosatrienoyl-CoA) Type: Regular Location: Cytosol KEGG ID: R09419;R10826;R10827;R10828 click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item 1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item 4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item 1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : lnlncgcoaName: gamma-linolenoyl-CoA Formula: C39H60N7O17P3S Charge: -4 click to see details on this item + malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (3) hName: H+ Formula: H Charge: 1 click to see details on this item	dlnlcgcoaName: dihomo-gamma-linolenyl coenzyme A Formula: C41H64N7O17P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	(elo-1 \| elo-2) & let-767 & hpo-8 & art-1	Fatty acid biosynthesis
RCC0063Name: long chain fatty acid elongation (Stearidonoyl-CoA to Icosatetraenoyl-CoA) Type: Regular Location: Cytosol KEGG ID: R10825;R10826;R10827;R10828 click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item 1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item 4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item 1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : strdnccoaName: stearidonyl coenzyme A Formula: C39H58N7O17P3S Charge: -4 click to see details on this item + malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (3) hName: H+ Formula: H Charge: 1 click to see details on this item	eicostetcoaName: eicosatetranoyl coenzyme A Formula: C41H62N7O17P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	(elo-1 \| elo-2) & let-767 & hpo-8 & art-1	Fatty acid biosynthesis
RCC0124Name: merged fatty acid elongation (C18 to C24) Type: Regular Location: Cytosol KEGG ID: R10825;R10826;R10827;R10828 click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item 1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item 4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item 1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : (9) hName: H+ Formula: H Charge: 1 click to see details on this item + (3) malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (6) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + stcoaName: Stearoyl-CoA (n-C18:0CoA) Formula: C39H66N7O17P3S Charge: -4 click to see details on this item	(3) co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + (3) coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (3) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (6) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + lgnccoaName: lignocericyl coenzyme A Formula: C45H78N7O17P3S Charge: -4 click to see details on this item	elo-1 & let-767 & hpo-8 & art-1	Fatty acid biosynthesis
RCC0210Name: Octacosanoic acid synthesis Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item 1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item 4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item 1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : lgnccoaName: lignocericyl coenzyme A Formula: C45H78N7O17P3S Charge: -4 click to see details on this item + (2) malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (4) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (6) hName: H+ Formula: H Charge: 1 click to see details on this item	fa28p0coaName: octacosanoyl-CoA Formula: C49H86N7O17P3S Charge: -4 click to see details on this item + (2) co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + (2) coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (2) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (4) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	elo-1 & let-767 & hpo-8 & art-1	Ascaroside biosynthesis
RCC0072Name: long chain fatty acid elongation (C13:iso to C15:iso) Type: Regular Location: Cytosol KEGG ID: R09419;R10826;R10827;R10828 click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item 1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item 4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item 1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : fa13p0isoName: Fatty acid (C13:iso) Formula: C13H25O2 Charge: -1 click to see details on this item + malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (3) hName: H+ Formula: H Charge: 1 click to see details on this item	fa15p0isoName: Fatty acid (C15:iso) Formula: C15H29O2 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	elo-5 & let-767 & hpo-8 & art-1	Fatty acid biosynthesis
RCC0073Name: long chain fatty acid elongation (C15:iso to C17:iso) Type: Regular Location: Cytosol KEGG ID: R09419;R10826;R10827;R10828 click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item 1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item 4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item 1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : fa15p0isoName: Fatty acid (C15:iso) Formula: C15H29O2 Charge: -1 click to see details on this item + malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (3) hName: H+ Formula: H Charge: 1 click to see details on this item	fa17p0isoName: Fatty acid (C17:iso) Formula: C17H33O2 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	(elo-5 \| elo-6) & let-767 & hpo-8 & art-1	Fatty acid biosynthesis
RC07760Name: 3-hydroxyacyl-CoA dehydratase 2 Type: Regular Location: Cytosol KEGG ID: R07760 click to see details on this item	4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item	[c] : 3hodcoaName: (S)-3-Hydroxyoctadecanoyl-CoA Formula: C39H66N7O18P3S Charge: -4 click to see details on this item	h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + od2coaName: trans-Octadec-2-enoyl-CoA Formula: C39H64N7O17P3S Charge: -4 click to see details on this item	hpo-8	Fatty acid biosynthesis
RCC0070Name: long chain fatty acid elongation (Palmitoleyl-coA to Vaccenyl-coA) Type: Regular Location: Cytosol KEGG ID: R09419;R10826;R10827;R10828 click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item 1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item 4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item 1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : fa16p1n7coaName: Palmitoleyl-coA Formula: C37H60N7O17P3S Charge: -4 click to see details on this item + malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (3) hName: H+ Formula: H Charge: 1 click to see details on this item	vacccoaName: Vaccenyl coenzyme A Formula: C39H64N7O17P3S Charge: -4 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	(elo-1 \| elo-2 \| elo-3 \| elo-4 \| elo-5 \| elo-6 \| elo-7 \| elo-9) & let-767 & hpo-8 & art-1	Fatty acid biosynthesis

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