HOME DOWNLOAD CITATION HELP
Umass Logo PSB Logo
(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 4.2.1.134
Name ..................................................... : Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, etc.PHS1 (gene name), PAS2 (gene name)
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K10703PHS1 PAS2; very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase [EC:4.2.1.134]
Genes ..................................................... : hpo-8
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below (8 reactions in total)
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RCC0210Name: Octacosanoic acid synthesis
Type: Regular
Location: Cytosol
KEGG ID: NA

click to see details on this item
2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase
Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name)

click to see details on this item
1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase
Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name)

click to see details on this item
4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase
Other names: PHS1 (gene name), PAS2 (gene name)

click to see details on this item
1.3.1.93Name: very-long-chain enoyl-CoA reductase
Other names: TSC13 (gene name), CER10 (gene name)

click to see details on this item
[c] : lgnccoaName: lignocericyl coenzyme A
Formula: C45H78N7O17P3S
Charge: -4




click to see details on this item + (2) malcoaName: Malonyl-CoA
Formula: C24H33N7O19P3S
Charge: -5




click to see details on this item + (4) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + (6) hName: H+
Formula: H
Charge: 1




click to see details on this item
fa28p0coaName: octacosanoyl-CoA
Formula: C49H86N7O17P3S
Charge: -4




click to see details on this item + (2) co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item + (2) coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + (2) h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + (4) nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item
elo-1 & let-767 & hpo-8 & art-1
Ascaroside biosynthesis
RCC0063Name: long chain fatty acid elongation (Stearidonoyl-CoA to Icosatetraenoyl-CoA)
Type: Regular
Location: Cytosol
KEGG ID: R10825;R10826;R10827;R10828

click to see details on this item
2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase
Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name)

click to see details on this item
1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase
Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name)

click to see details on this item
4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase
Other names: PHS1 (gene name), PAS2 (gene name)

click to see details on this item
1.3.1.93Name: very-long-chain enoyl-CoA reductase
Other names: TSC13 (gene name), CER10 (gene name)

click to see details on this item
[c] : strdnccoaName: stearidonyl coenzyme A
Formula: C39H58N7O17P3S
Charge: -4




click to see details on this item + malcoaName: Malonyl-CoA
Formula: C24H33N7O19P3S
Charge: -5




click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + (3) hName: H+
Formula: H
Charge: 1




click to see details on this item
eicostetcoaName: eicosatetranoyl coenzyme A
Formula: C41H62N7O17P3S
Charge: -4




click to see details on this item + coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item
(elo-1 | elo-2) & let-767 & hpo-8 & art-1
Fatty acid biosynthesis
RCC0064Name: long chain fatty acid elongation (Linolenoyl-CoA to Eicosatrienoyl-CoA)
Type: Regular
Location: Cytosol
KEGG ID: R09419;R10826;R10827;R10828

click to see details on this item
2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase
Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name)

click to see details on this item
1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase
Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name)

click to see details on this item
4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase
Other names: PHS1 (gene name), PAS2 (gene name)

click to see details on this item
1.3.1.93Name: very-long-chain enoyl-CoA reductase
Other names: TSC13 (gene name), CER10 (gene name)

click to see details on this item
[c] : lnlncgcoaName: gamma-linolenoyl-CoA
Formula: C39H60N7O17P3S
Charge: -4




click to see details on this item + malcoaName: Malonyl-CoA
Formula: C24H33N7O19P3S
Charge: -5




click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + (3) hName: H+
Formula: H
Charge: 1




click to see details on this item
dlnlcgcoaName: dihomo-gamma-linolenyl coenzyme A
Formula: C41H64N7O17P3S
Charge: -4




click to see details on this item + coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item
(elo-1 | elo-2) & let-767 & hpo-8 & art-1
Fatty acid biosynthesis
RCC0070Name: long chain fatty acid elongation (Palmitoleyl-coA to Vaccenyl-coA)
Type: Regular
Location: Cytosol
KEGG ID: R09419;R10826;R10827;R10828

click to see details on this item
2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase
Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name)

click to see details on this item
1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase
Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name)

click to see details on this item
4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase
Other names: PHS1 (gene name), PAS2 (gene name)

click to see details on this item
1.3.1.93Name: very-long-chain enoyl-CoA reductase
Other names: TSC13 (gene name), CER10 (gene name)

click to see details on this item
[c] : fa16p1n7coaName: Palmitoleyl-coA
Formula: C37H60N7O17P3S
Charge: -4




click to see details on this item + malcoaName: Malonyl-CoA
Formula: C24H33N7O19P3S
Charge: -5




click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + (3) hName: H+
Formula: H
Charge: 1




click to see details on this item
vacccoaName: Vaccenyl coenzyme A
Formula: C39H64N7O17P3S
Charge: -4




click to see details on this item + coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item
(elo-1 | elo-2 | elo-3 | elo-4 | elo-5 | elo-6 | elo-7 | elo-9) & let-767 & hpo-8 & art-1
Fatty acid biosynthesis
RC07760Name: 3-hydroxyacyl-CoA dehydratase 2
Type: Regular
Location: Cytosol
KEGG ID: R07760

click to see details on this item
4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase
Other names: PHS1 (gene name), PAS2 (gene name)

click to see details on this item
[c] : 3hodcoaName: (S)-3-Hydroxyoctadecanoyl-CoA
Formula: C39H66N7O18P3S
Charge: -4




click to see details on this item
h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + od2coaName: trans-Octadec-2-enoyl-CoA
Formula: C39H64N7O17P3S
Charge: -4




click to see details on this item
hpo-8
Fatty acid biosynthesis
RCC0124Name: merged fatty acid elongation (C18 to C24)
Type: Regular
Location: Cytosol
KEGG ID: R10825;R10826;R10827;R10828

click to see details on this item
2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase
Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name)

click to see details on this item
1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase
Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name)

click to see details on this item
4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase
Other names: PHS1 (gene name), PAS2 (gene name)

click to see details on this item
1.3.1.93Name: very-long-chain enoyl-CoA reductase
Other names: TSC13 (gene name), CER10 (gene name)

click to see details on this item
[c] : (9) hName: H+
Formula: H
Charge: 1




click to see details on this item + (3) malcoaName: Malonyl-CoA
Formula: C24H33N7O19P3S
Charge: -5




click to see details on this item + (6) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + stcoaName: Stearoyl-CoA (n-C18:0CoA)
Formula: C39H66N7O17P3S
Charge: -4




click to see details on this item
(3) co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item + (3) coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + (3) h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + (6) nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + lgnccoaName: lignocericyl coenzyme A
Formula: C45H78N7O17P3S
Charge: -4




click to see details on this item
elo-1 & let-767 & hpo-8 & art-1
Fatty acid biosynthesis
RCC0072Name: long chain fatty acid elongation (C13:iso to C15:iso)
Type: Regular
Location: Cytosol
KEGG ID: R09419;R10826;R10827;R10828

click to see details on this item
2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase
Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name)

click to see details on this item
1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase
Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name)

click to see details on this item
4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase
Other names: PHS1 (gene name), PAS2 (gene name)

click to see details on this item
1.3.1.93Name: very-long-chain enoyl-CoA reductase
Other names: TSC13 (gene name), CER10 (gene name)

click to see details on this item
[c] : fa13p0isoName: Fatty acid (C13:iso)
Formula: C13H25O2
Charge: -1




click to see details on this item + malcoaName: Malonyl-CoA
Formula: C24H33N7O19P3S
Charge: -5




click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + (3) hName: H+
Formula: H
Charge: 1




click to see details on this item
fa15p0isoName: Fatty acid (C15:iso)
Formula: C15H29O2
Charge: -1




click to see details on this item + coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item
elo-5 & let-767 & hpo-8 & art-1
Fatty acid biosynthesis
RCC0073Name: long chain fatty acid elongation (C15:iso to C17:iso)
Type: Regular
Location: Cytosol
KEGG ID: R09419;R10826;R10827;R10828

click to see details on this item
2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase
Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name)

click to see details on this item
1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase
Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name)

click to see details on this item
4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase
Other names: PHS1 (gene name), PAS2 (gene name)

click to see details on this item
1.3.1.93Name: very-long-chain enoyl-CoA reductase
Other names: TSC13 (gene name), CER10 (gene name)

click to see details on this item
[c] : fa15p0isoName: Fatty acid (C15:iso)
Formula: C15H29O2
Charge: -1




click to see details on this item + malcoaName: Malonyl-CoA
Formula: C24H33N7O19P3S
Charge: -5




click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + (3) hName: H+
Formula: H
Charge: 1




click to see details on this item
fa17p0isoName: Fatty acid (C17:iso)
Formula: C17H33O2
Charge: -1




click to see details on this item + coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




click to see details on this item
(elo-5 | elo-6) & let-767 & hpo-8 & art-1
Fatty acid biosynthesis
The information and tools provided in this website are to be used for academic purposes only.