WormFlux: mechanistic analysis of C. elegans metabolism

HOME DOWNLOAD CITATION HELP

(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	fa13p0iso
Name .....................................................	:	Fatty acid (C13:iso)
Model ID .....................................................	:	CC0069
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	Not available
Formula .....................................................	:	C13H25O2
Charge .....................................................	:	-1
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	fa9, fa6, fa5, fa4, fa3, fa20n, fa19a, fa12, fa11, fa10, fa1
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Fatty acid biosynthesis (c)

iCEL1314

Comments

See CC0067 for custom fatty acid nomenclature.

Iso stands for isomer.

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0071Name: branched-chain fatty acid synthase Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	2.3.1.85Name: fatty-acid synthase Other names: FASN (gene name) click to see details on this item	[c] : (11) hName: H+ Formula: H Charge: 1 click to see details on this item + ivcoaName: Isovaleryl-CoA Formula: C26H40N7O17P3S Charge: -4 click to see details on this item + (4) malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (8) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		(4) co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + (5) coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + fa13p0isoName: Fatty acid (C13:iso) Formula: C13H25O2 Charge: -1 click to see details on this item + (3) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + (8) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	fasn-1	Fatty acid biosynthesis
RCC0072Name: long chain fatty acid elongation (C13:iso to C15:iso) Type: Regular Location: Cytosol KEGG ID: R09419;R10826;R10827;R10828 click to see details on this item	2.3.1.199Name: very-long-chain 3-oxoacyl-CoA synthase Other names: very-long-chain 3-ketoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase, condensing enzyme, CUT1 (gene name), CER6 (gene name), FAE1 (gene name), KCS (gene name), ELO (gene name) click to see details on this item 1.1.1.330Name: very-long-chain 3-oxoacyl-CoA reductase Other names: very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene name), IFA38 (gene name) click to see details on this item 4.2.1.134Name: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase Other names: PHS1 (gene name), PAS2 (gene name) click to see details on this item 1.3.1.93Name: very-long-chain enoyl-CoA reductase Other names: TSC13 (gene name), CER10 (gene name) click to see details on this item	[c] : fa13p0isoName: Fatty acid (C13:iso) Formula: C13H25O2 Charge: -1 click to see details on this item + malcoaName: Malonyl-CoA Formula: C24H33N7O19P3S Charge: -5 click to see details on this item + (2) nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item + (3) hName: H+ Formula: H Charge: 1 click to see details on this item		fa15p0isoName: Fatty acid (C15:iso) Formula: C15H29O2 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + (2) nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	elo-5 & let-767 & hpo-8 & art-1	Fatty acid biosynthesis

The information and tools provided in this website are to be used for academic purposes only.