WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	gal
Name .....................................................	:	D-Galactose, etc.D-Galactopyranose
Model ID .....................................................	:	C00124
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00124
Formula .....................................................	:	C6H12O6
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	gal
Other associations .....................................................	:	See reaction table below (12 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Galactose metabolism (c), Sphingolipid metabolism (c)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01092Name: ATP:D-galactose 1-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01092 click to see details on this item	2.7.1.6Name: galactokinase Other names: galactokinase (phosphorylating), ATP:D-galactose-1-phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + gal1pName: alpha-D-Galactose 1-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	tag-96	Galactose metabolism
RC01093Name: galactitol:NAD+ 1-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01093 click to see details on this item	1.1.1.21Name: aldehyde reductase Other names: aldose reductase, polyol dehydrogenase (NADP+), ALR2, alditol:NADP+ oxidoreductase, alditol:NADP+ 1-oxidoreductase, NADPH-aldopentose reductase, NADPH-aldose reductase click to see details on this item	[c] : galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item		galtName: Galactitol Formula: C6H14O6 Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item	Y39G8B.1	Galactose metabolism
RC01095Name: galactitol:NADP+ 1-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01095 click to see details on this item	1.1.1.21Name: aldehyde reductase Other names: aldose reductase, polyol dehydrogenase (NADP+), ALR2, alditol:NADP+ oxidoreductase, alditol:NADP+ 1-oxidoreductase, NADPH-aldopentose reductase, NADPH-aldose reductase click to see details on this item	[c] : galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		galtName: Galactitol Formula: C6H14O6 Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	Y39G8B.1	Galactose metabolism
RC01100Name: Lactose galactohydrolase Type: Regular Location: Cytosol KEGG ID: R01100 click to see details on this item	3.2.1.23Name: beta-galactosidase Other names: lactase (ambiguous), beta-lactosidase, maxilact, hydrolact, beta-D-lactosidase, S 2107, lactozym, trilactase, beta-D-galactanase, oryzatym, sumiklat click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + lctsName: Lactose Formula: C12H22O11 Charge: 0 click to see details on this item		galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item + glc-DName: D-Glucose Formula: C6H12O6 Charge: 0 click to see details on this item	bgal-1	Galactose metabolism
RC01101Name: melibiose galactohydrolase Type: Regular Location: Cytosol KEGG ID: R01101 click to see details on this item	3.2.1.22Name: alpha-galactosidase Other names: melibiase, alpha-D-galactosidase, alpha-galactosidase A, alpha-galactoside galactohydrolase click to see details on this item	[c] : melibName: Melibiose Formula: C12H22O11 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item + glc-DName: D-Glucose Formula: C6H12O6 Charge: 0 click to see details on this item	gana-1	Galactose metabolism
RC01103Name: Raffinose galactohydrolase Type: Regular Location: Cytosol KEGG ID: R01103 click to see details on this item	3.2.1.22Name: alpha-galactosidase Other names: melibiase, alpha-D-galactosidase, alpha-galactosidase A, alpha-galactoside galactohydrolase click to see details on this item	[c] : raffinName: Raffinose Formula: C18H32O16 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item + sucrName: Sucrose Formula: C12H22O11 Charge: 0 click to see details on this item	gana-1	Galactose metabolism
RC03634Name: Stachyose galactohydrolase Type: Regular Location: Cytosol KEGG ID: R03634 click to see details on this item	3.2.1.22Name: alpha-galactosidase Other names: melibiase, alpha-D-galactosidase, alpha-galactosidase A, alpha-galactoside galactohydrolase click to see details on this item	[c] : stachyoseName: Stachyose Formula: C24H42O21 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		raffinName: Raffinose Formula: C18H32O16 Charge: 0 click to see details on this item + galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item	gana-1	Galactose metabolism
RC03618Name: Trihexosylceramide galactohydrolase Type: Regular Location: Cytosol KEGG ID: R03618 click to see details on this item	3.2.1.22Name: alpha-galactosidase Other names: melibiase, alpha-D-galactosidase, alpha-galactosidase A, alpha-galactoside galactohydrolase click to see details on this item	[c] : thcrm_ceName: trihexosyl ceramide Formula: C37H68NO17FULLRCO Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item + galgluside_ceName: galactosyl glucosyl ceramide Formula: C31H58NO12FULLRCO Charge: 0 click to see details on this item	gana-1	Galactose metabolism
RC03617Name: D-galactosyl-N-acylsphingosine galactohydrolase Type: Regular Location: Cytosol KEGG ID: R03617 click to see details on this item	3.2.1.46Name: galactosylceramidase Other names: cerebroside galactosidase, galactocerebroside.beta-galactosidase, galactosylcerebrosidase, galactocerebrosidase, ceramide galactosidase, galactocerebroside galactosidase, galactosylceramide.beta-galactosidase, cerebroside beta-galactosidase, galactosylceramidase I, beta-galactosylceramidase, galactocerebroside-beta-D-galactosidase, lactosylceramidase I, beta-galactocerebrosidase, lactosylceramidase click to see details on this item	[c] : galside_ceName: galactocerebroside Formula: C25H48NO7FULLRCO Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		crm_ceName: ceramide Formula: C19H38NO2FULLRCO Charge: 0 click to see details on this item + galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item	C29E4.10	Sphingolipid metabolism
RC06099Name: beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase Type: Regular Location: Cytosol KEGG ID: R06099 click to see details on this item	3.2.1.23Name: beta-galactosidase Other names: lactase (ambiguous), beta-lactosidase, maxilact, hydrolact, beta-D-lactosidase, S 2107, lactozym, trilactase, beta-D-galactanase, oryzatym, sumiklat click to see details on this item	[c] : galgluside_ceName: galactosyl glucosyl ceramide Formula: C31H58NO12FULLRCO Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		gluside_ceName: glucocerebroside Formula: C25H48NO7FULLRCO Charge: 0 click to see details on this item + galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item	bgal-1 \| bgal-2	Galactose metabolism
TCE0338Name: D-Galactose transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item[e]		galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item[c]	Not determined	Transport
EX00124Name: D-Galactose exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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