WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	lcts
Name .....................................................	:	Lactose, etc.1-beta-D-Galactopyranosyl-4-D-glucopyranose, beta-D-Gal-(1->4)-D-Glc, Milk sugar
Model ID .....................................................	:	C00243
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00243
Formula .....................................................	:	C12H22O11
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	lcts
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Galactose metabolism (c,e)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01100Name: Lactose galactohydrolase Type: Regular Location: Cytosol KEGG ID: R01100 click to see details on this item	3.2.1.23Name: beta-galactosidase Other names: lactase (ambiguous), beta-lactosidase, maxilact, hydrolact, beta-D-lactosidase, S 2107, lactozym, trilactase, beta-D-galactanase, oryzatym, sumiklat click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + lctsName: Lactose Formula: C12H22O11 Charge: 0 click to see details on this item		galName: D-Galactose Formula: C6H12O6 Charge: 0 click to see details on this item + glc-DName: D-Glucose Formula: C6H12O6 Charge: 0 click to see details on this item	bgal-1	Galactose metabolism
TCE5041Name: Lactose transport via proton symport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	lctsName: Lactose Formula: C12H22O11 Charge: 0 click to see details on this item[e]		lctsName: Lactose Formula: C12H22O11 Charge: 0 click to see details on this item[c]	Not determined	Transport
EX00243Name: Lactose exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	lctsName: Lactose Formula: C12H22O11 Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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