WormFlux: mechanistic analysis of C. elegans metabolism

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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	1.11.1.9
Name .....................................................	:	Glutathione peroxidase, etc.GSH peroxidase, Selenium-glutathione peroxidase, Reduced glutathione peroxidase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K00432E1.11.1.9; glutathione peroxidase [EC:1.11.1.9]
Genes .....................................................	:	gpx-1, gpx-2, gpx-3, gpx-4, gpx-5, gpx-7, gpx-8
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC07034Name: Glutathione: 5-HPETE oxidoreductase Type: Regular Location: Cytosol KEGG ID: R07034 click to see details on this item	1.11.1.9Name: glutathione peroxidase Other names: GSH peroxidase, selenium-glutathione peroxidase, reduced glutathione peroxidase click to see details on this item	[c] : (2) gthrdName: Reduced glutathione Formula: C10H16N3O6S Charge: -1 click to see details on this item + 5HPETName: "5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate" Formula: C20H31O4 Charge: -1 click to see details on this item		gthoxName: Oxidized glutathione Formula: C20H30N6O12S2 Charge: -2 click to see details on this item + 5HETEName: 5-Hydroxyeicosatetraenoate Formula: C20H31O3 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	gpx-1 \| gpx-2 \| gpx-3 \| gpx-4 \| gpx-5 \| gpx-7 \| gpx-8	Arachidonic acid metabolism
RC00274Name: glutathione:hydrogen-peroxide oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00274 click to see details on this item	1.11.1.9Name: glutathione peroxidase Other names: GSH peroxidase, selenium-glutathione peroxidase, reduced glutathione peroxidase click to see details on this item	[c] : (2) gthrdName: Reduced glutathione Formula: C10H16N3O6S Charge: -1 click to see details on this item + h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item		gthoxName: Oxidized glutathione Formula: C20H30N6O12S2 Charge: -2 click to see details on this item + (2) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	gpx-1 \| gpx-2 \| gpx-3 \| gpx-4 \| gpx-5 \| gpx-7 \| gpx-8	Glutathione metabolism

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