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Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Metabolite Overview
Abbreviation ..................................................... : sphgn_ce
Name ..................................................... : Sphinganine
Model ID ..................................................... : CC0207
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : Not available
Formula ..................................................... : C19H42NO2
Charge ..................................................... : +1
Localization ..................................................... : Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : sphgn
Other associations ..................................................... : See reaction table below (7 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Sphingolipid metabolism (c)
Comments
  • Charge based on matching BiGG compound.

    • Reactions
    ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

    I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
    & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

    If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.     		Pathway
    RC06517Name: acyl-CoA:sphingosine N-acyltransferase
    Type: Regular
    Location: Cytosol
    KEGG ID: R06517

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    2.3.1.24Name: sphingosine N-acyltransferase
    Other names: ceramide synthetase, sphingosine acyltransferase

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    [c] : RtotalcoaName: R total Coenzyme A
    Formula: CO2FULLRC21H31N7O15P3S
    Charge: -4




    click to see details on this item     + sphgn_ceName: Sphinganine
    Formula: C19H42NO2
    Charge: 1




    click to see details on this item
    coaName: Coenzyme A
    Formula: C21H32N7O16P3S
    Charge: -4




    click to see details on this item     + dhcrm_ceName: dihydroceramide
    Formula: C19H40NO2FULLRCO
    Charge: 0




    click to see details on this item     + hName: H+
    Formula: H
    Charge: 1




    click to see details on this item
    hyl-1 | hyl-2 | lagr-1
    Sphingolipid metabolism
    RC06518Name: N-acylsphingosine amidohydrolase
    Type: Regular
    Location: Cytosol
    KEGG ID: R06518

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    3.5.1.23Name: ceramidase
    Other names: acylsphingosine deacylase, glycosphingolipid ceramide deacylase

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    [c] : dhcrm_ceName: dihydroceramide
    Formula: C19H40NO2FULLRCO
    Charge: 0




    click to see details on this item     + h2oName: H2O
    Formula: H2O
    Charge: 0




    click to see details on this item
    RtotalName: R total
    Formula: CO2FULLR
    Charge: -1




    click to see details on this item     + sphgn_ceName: Sphinganine
    Formula: C19H42NO2
    Charge: 1




    click to see details on this item
    W02F12.2
    Sphingolipid metabolism
    RC02976Name: sphinganine kinase
    Type: Regular
    Location: Cytosol
    KEGG ID: R02976

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    2.7.1.91Name: sphinganine kinase
    Other names: dihydrosphingosine kinase, dihydrosphingosine kinase (phosphorylating), sphingosine kinase (phosphorylating)

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    [c] : atpName: ATP
    Formula: C10H12N5O13P3
    Charge: -4




    click to see details on this item     + sphgn_ceName: Sphinganine
    Formula: C19H42NO2
    Charge: 1




    click to see details on this item
    adpName: ADP
    Formula: C10H12N5O10P2
    Charge: -3




    click to see details on this item     + hName: H+
    Formula: H
    Charge: 1




    click to see details on this item     + sph1p_ceName: Sphinganine 1-phosphate
    Formula: C19H41NO5P
    Charge: -1




    click to see details on this item
    sphk-1
    Sphingolipid metabolism
    RC02978Name: 3-dehydrosphinganine reductase
    Type: Regular
    Location: Cytosol
    KEGG ID: R02978

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    1.1.1.102Name: 3-dehydrosphinganine reductase
    Other names: D-3-dehydrosphinganine reductase, D-3-oxosphinganine reductase, DSR, 3-oxosphinganine reductase, 3-oxosphinganine:NADPH oxidoreductase, D-3-oxosphinganine:B-NADPH oxidoreductase

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    [c] : 3dsphgn_ceName: 3-Dehydrosphinganine
    Formula: C19H40NO2
    Charge: 1




    click to see details on this item     + hName: H+
    Formula: H
    Charge: 1




    click to see details on this item     + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
    Formula: C21H26N7O17P3
    Charge: -4




    click to see details on this item
    nadpName: Nicotinamide adenine dinucleotide phosphate
    Formula: C21H25N7O17P3
    Charge: -3




    click to see details on this item     + sphgn_ceName: Sphinganine
    Formula: C19H42NO2
    Charge: 1




    click to see details on this item
    To be determined
    Sphingolipid metabolism
    RC06520Name: Sphinganine 1-phosphate phosphohydrolase
    Type: Regular
    Location: Cytosol
    KEGG ID: R06520

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    3.1.3.4Name: phosphatidate phosphatase
    Other names: phosphatic acid phosphatase, acid phosphatidyl phosphatase, phosphatic acid phosphohydrolase, PAP, Lipin

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    [c] : h2oName: H2O
    Formula: H2O
    Charge: 0




    click to see details on this item     + sph1p_ceName: Sphinganine 1-phosphate
    Formula: C19H41NO5P
    Charge: -1




    click to see details on this item
    piName: Phosphate
    Formula: HO4P
    Charge: -2




    click to see details on this item     + sphgn_ceName: Sphinganine
    Formula: C19H42NO2
    Charge: 1




    click to see details on this item
    F13E6.5 | F53C3.13 | T28D9.3
    Sphingolipid metabolism
    TCE5398Name: Sphinganine transport
    Type: Transport
    Location: Cytosol, Extracellular
    KEGG ID: NA

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    Not applicable
    sphgn_ceName: Sphinganine
    Formula: C19H42NO2
    Charge: 1




    click to see details on this item    [e]
    sphgn_ceName: Sphinganine
    Formula: C19H42NO2
    Charge: 1




    click to see details on this item    [c]
    Not determined
    Transport
    EXC0207Name: Sphinganine exchange
    Type: Exchange
    Location: Extracellular
    KEGG ID: NA

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    Not applicable
    sphgn_ceName: Sphinganine
    Formula: C19H42NO2
    Charge: 1




    click to see details on this item    [e]
    Not applicable
    Exchange with the environment
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