Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	3mgcoa
Name .....................................................	:	3-Methylglutaconyl-CoA, etc.trans-3-Methylglutaconyl-CoA, (E)-3-Methylglutaconyl-1-CoA
Model ID .....................................................	:	C03231
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C03231
Formula .....................................................	:	C27H37N7O19P3S
Charge .....................................................	:	-5
Localization .....................................................	:	Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	3mgcoa
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Leucine degradation (m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM04138Name: 3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) Type: Regular Location: Mitochondria KEGG ID: R04138 click to see details on this item	6.4.1.4Name: methylcrotonoyl-CoA carboxylase Other names: methylcrotonyl coenzyme A carboxylase, beta-methylcrotonyl coenzyme A carboxylase, beta-methylcrotonyl CoA carboxylase, methylcrotonyl-CoA carboxylase click to see details on this item	[m] : 3mb2coaName: 3-Methylbut-2-enoyl-CoA Formula: C26H38N7O17P3S Charge: -4 click to see details on this item + atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + hco3Name: Bicarbonate Formula: CHO3 Charge: -1 click to see details on this item		3mgcoaName: 3-Methylglutaconyl-CoA Formula: C27H37N7O19P3S Charge: -5 click to see details on this item + adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	mccc-1 & F02A9.4	Leucine degradation
RM02085Name: (S)-3-Hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming) Type: Regular Location: Mitochondria KEGG ID: R02085 click to see details on this item	4.2.1.18Name: methylglutaconyl-CoA hydratase Other names: methylglutaconyl coenzyme A hydratase, 3-methylglutaconyl CoA hydratase, methylglutaconase, (S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase click to see details on this item	[m] : 3mgcoaName: 3-Methylglutaconyl-CoA Formula: C27H37N7O19P3S Charge: -5 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		hmgcoaName: Hydroxymethylglutaryl-CoA Formula: C27H39N7O20P3S Charge: -5 click to see details on this item	ech-5	Leucine degradation

The information and tools provided in this website are to be used for academic purposes only.