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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 3.5.1.-
Name ..................................................... : NAD nucleosidase, etc.NAD-dependent histone deacetylase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K08281pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-], K11121SIR2; NAD-dependent histone deacetylase SIR2 [EC:3.5.1.-]
Genes ..................................................... : pnc-1, pnc-2, sir-2.1, sir-2.2, sir-2.3, sir-2.4
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC00102Name: NAD nucleosidase
Type: Regular
Location: Cytosol
KEGG ID: R00102

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3.5.1.-Name: nAD nucleosidase
Other names: nAD-dependent histone deacetylase

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[c] : h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




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adpribName: ADPribose
Formula: C15H21N5O14P2
Charge: -2




click to see details on this item + hName: H+
Formula: H
Charge: 1




click to see details on this item + ncamName: Nicotinamide
Formula: C6H6N2O
Charge: 0




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sir-2.1 | sir-2.2 | sir-2.3 | sir-2.4
Nicotinate and nicotinamide metabolism
RC10633Name: NAD-dependent histone deacetylase
Type: Regular
Location: Cytosol
KEGG ID: R10633

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3.5.1.-Name: nAD nucleosidase
Other names: nAD-dependent histone deacetylase

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[c] : nadName: Nicotinamide adenine dinucleotide
Formula: C21H26N7O14P2
Charge: -1




click to see details on this item + NaclysName: Histone N6-acetyl-L-lysine
Formula: XC8H14N2O2
Charge: 0




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




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ncamName: Nicotinamide
Formula: C6H6N2O
Charge: 0




click to see details on this item + NlysName: Histone-L-Lysine
Formula: XC6H13N2O
Charge: 1




click to see details on this item + ac_adpribName: O-Acetyl-ADP-ribose
Formula: C17H23N5O15P2
Charge: -2




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sir-2.1 | sir-2.2 | sir-2.3 | sir-2.4
Nicotinate and nicotinamide metabolism
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