WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	adprib
Name .....................................................	:	ADPribose, etc.ADP-ribose, ADP-D-ribose, Adenosine diphosphate ribose
Model ID .....................................................	:	C00301
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00301
Formula .....................................................	:	C15H21N5O14P2
Charge .....................................................	:	-2
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	adprib
Other associations .....................................................	:	See reaction table below (6 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Nicotinate and nicotinamide metabolism (c), Purine metabolism (c)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00102Name: NAD nucleosidase Type: Regular Location: Cytosol KEGG ID: R00102 click to see details on this item	3.5.1.-Name: nAD nucleosidase Other names: nAD-dependent histone deacetylase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		adpribName: ADPribose Formula: C15H21N5O14P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + ncamName: Nicotinamide Formula: C6H6N2O Charge: 0 click to see details on this item	sir-2.1 \| sir-2.2 \| sir-2.3 \| sir-2.4	Nicotinate and nicotinamide metabolism
RCC0051Name: poly(ADP-ribose) glycohydrolase (PARG) Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	3.2.1.143Name: poly(ADP-ribose) glycohydrolase click to see details on this item	[c] : polyadpribName: poly adp ribose Formula: C15H19N5O13P2 Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		adpribName: ADPribose Formula: C15H21N5O14P2 Charge: -2 click to see details on this item	parg-1 \| parg-2	Nicotinate and nicotinamide metabolism
RCC0163Name: O-acetyl-ADP-ribose deacetylase Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	[c] : ac_adpribName: O-Acetyl-ADP-ribose Formula: C17H23N5O15P2 Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		adpribName: ADPribose Formula: C15H21N5O14P2 Charge: -2 click to see details on this item + acName: Acetate Formula: C2H3O2 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	Unknown	Miscellaneous
RC01054Name: ADP-ribose ribophosphohydrolase Type: Regular Location: Cytosol KEGG ID: R01054 click to see details on this item	3.6.1.13Name: ADP-ribose diphosphatase Other names: ADPribose pyrophosphatase, adenosine diphosphoribose pyrophosphatase, ADPR-PPase, ADP-ribose ribophosphohydrolase click to see details on this item	[c] : adpribName: ADPribose Formula: C15H21N5O14P2 Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + r5pName: alpha-D-Ribose 5-phosphate Formula: C5H9O8P Charge: -2 click to see details on this item	ndx-2 \| ndx-6	Purine metabolism
TCE0739Name: ADPribose transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	adpribName: ADPribose Formula: C15H21N5O14P2 Charge: -2 click to see details on this item[e]		adpribName: ADPribose Formula: C15H21N5O14P2 Charge: -2 click to see details on this item[c]	Not determined	Transport
EX00301Name: ADPribose exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	adpribName: ADPribose Formula: C15H21N5O14P2 Charge: -2 click to see details on this item[e]			Not applicable	Exchange with the environment

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