WormFlux: mechanistic analysis of C. elegans metabolism

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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	2.7.1.1
Name .....................................................	:	Hexokinase, etc.Hexokinase type IV glucokinase, Hexokinase D, Hexokinase type IV, Hexokinase (phosphorylating), ATP-dependent hexokinase, Glucose ATP phosphotransferase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K00844HK; hexokinase [EC:2.7.1.1]
Genes .....................................................	:	hxk-1, hxk-2, hxk-3
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01961Name: ATP:D-glucosamine 6-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01961 click to see details on this item	2.7.1.1Name: hexokinase Other names: hexokinase type IV glucokinase, hexokinase D, hexokinase type IV, hexokinase (phosphorylating), ATP-dependent hexokinase, glucose ATP phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + gamName: D-Glucosamine Formula: C6H14NO5 Charge: 1 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + gam6pName: D-Glucosamine 6-phosphate Formula: C6H13NO8P Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hxk-1 \| hxk-2 \| hxk-3	Amino sugar and nucleotide sugar metabolism
RC01326Name: ATP:D-mannose 6-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01326 click to see details on this item	2.7.1.1Name: hexokinase Other names: hexokinase type IV glucokinase, hexokinase D, hexokinase type IV, hexokinase (phosphorylating), ATP-dependent hexokinase, glucose ATP phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + manName: D-Mannose Formula: C6H12O6 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + man6pName: D-Mannose 6-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item	hxk-1 \| hxk-2 \| hxk-3	Fructose and mannose metabolism
RC00867Name: ATP:D-fructose 6-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00867 click to see details on this item	2.7.1.1Name: hexokinase Other names: hexokinase type IV glucokinase, hexokinase D, hexokinase type IV, hexokinase (phosphorylating), ATP-dependent hexokinase, glucose ATP phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + fruName: D-Fructose Formula: C6H12O6 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + f6pName: D-Fructose 6-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hxk-1 \| hxk-2 \| hxk-3	Amino sugar and nucleotide sugar metabolism
RC01600Name: ATP:beta-D-glucose 6-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01600 click to see details on this item	2.7.1.1Name: hexokinase Other names: hexokinase type IV glucokinase, hexokinase D, hexokinase type IV, hexokinase (phosphorylating), ATP-dependent hexokinase, glucose ATP phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + glc-D-BName: beta-D-Glucose Formula: C6H12O6 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + g6p-BName: beta-D-glucose 6-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hxk-1 \| hxk-2 \| hxk-3	Amino sugar and nucleotide sugar metabolism
RC01786Name: ATP:alpha-D-glucose 6-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01786 click to see details on this item	2.7.1.1Name: hexokinase Other names: hexokinase type IV glucokinase, hexokinase D, hexokinase type IV, hexokinase (phosphorylating), ATP-dependent hexokinase, glucose ATP phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + glc-D-AName: alpha-D-Glucose Formula: C6H12O6 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + g6p-AName: alpha-D-Glucose 6-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hxk-1 \| hxk-2 \| hxk-3	Amino sugar and nucleotide sugar metabolism

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