Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	man
Name .....................................................	:	D-Mannose, etc.Mannose, Seminose, Carubinose
Model ID .....................................................	:	C00159
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00159
Formula .....................................................	:	C6H12O6
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	man
Other associations .....................................................	:	See reaction table below (6 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Fructose and mannose metabolism (c), N-Glycan biosynthesis (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01326Name: ATP:D-mannose 6-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R01326 click to see details on this item	2.7.1.1Name: hexokinase Other names: hexokinase type IV glucokinase, hexokinase D, hexokinase type IV, hexokinase (phosphorylating), ATP-dependent hexokinase, glucose ATP phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + manName: D-Mannose Formula: C6H12O6 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + man6pName: D-Mannose 6-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item	hxk-1 | hxk-2 | hxk-3	Fructose and mannose metabolism
RC05982Name: mannosyl-oligosaccharide 1,2-alpha-mannosidase Type: Regular Location: Cytosol KEGG ID: R05982 click to see details on this item	3.2.1.113Name: mannosyl-oligosaccharide 1,2-alpha-mannosidase Other names: mannosidase 1A, mannosidase 1B, 1,2-alpha-mannosidase, exo-alpha-1,2-mannanase, mannose-9 processing alpha-mannosidase, glycoprotein processing mannosidase I, mannosidase I, Man9-mannosidase, ManI, 1,2-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase click to see details on this item	[c] : m8masnName: (alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein) Formula: C70H117N2O55X Charge: 0 click to see details on this item + (4) h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		m4masnName: (alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein) Formula: C46H77N2O35X Charge: 0 click to see details on this item + (4) manName: D-Mannose Formula: C6H12O6 Charge: 0 click to see details on this item	mans-1 | mans-2 | mans-3 | mans-4	N-Glycan biosynthesis
RCC0038Name: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (acting on nm4masn) Type: Regular Location: Cytosol KEGG ID: R05984 click to see details on this item	3.2.1.114Name: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase Other names: mannosidase II, exo-1,3-1,6-alpha-mannosidase, alpha-D-mannosidase II, alpha-mannosidase II, alpha1-3,6-mannosidase, GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase, Golgi alpha-mannosidase II, ManII, 1,3(1,6)-alpha-D-mannosidase, 1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nm4masnName: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein) Formula: C54H90N3O40X Charge: 0 click to see details on this item		manName: D-Mannose Formula: C6H12O6 Charge: 0 click to see details on this item + nm3masnName: M4Gn3 Formula: C48H80N3O35X Charge: 0 click to see details on this item	aman-2	N-Glycan biosynthesis
RCC0039Name: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (acting on nm3masn) Type: Regular Location: Cytosol KEGG ID: R05984 click to see details on this item	3.2.1.114Name: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase Other names: mannosidase II, exo-1,3-1,6-alpha-mannosidase, alpha-D-mannosidase II, alpha-mannosidase II, alpha1-3,6-mannosidase, GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase, Golgi alpha-mannosidase II, ManII, 1,3(1,6)-alpha-D-mannosidase, 1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nm3masnName: M4Gn3 Formula: C48H80N3O35X Charge: 0 click to see details on this item		manName: D-Mannose Formula: C6H12O6 Charge: 0 click to see details on this item + nm2masnName: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein) Formula: C42H70N3O30X Charge: 0 click to see details on this item	aman-2	N-Glycan biosynthesis
TCE0424Name: D-Mannose transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	manName: D-Mannose Formula: C6H12O6 Charge: 0 click to see details on this item[e]		manName: D-Mannose Formula: C6H12O6 Charge: 0 click to see details on this item[c]	Not determined	Transport
EX00159Name: D-Mannose exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	manName: D-Mannose Formula: C6H12O6 Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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