WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	fru
Name .....................................................	:	D-Fructose, etc.Levulose, Fruit sugar, D-arabino-Hexulose
Model ID .....................................................	:	C00095
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00095
Formula .....................................................	:	C6H12O6
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	fru
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Amino sugar and nucleotide sugar metabolism (c), Fructose and mannose metabolism (c), Galactose metabolism (c)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00867Name: ATP:D-fructose 6-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00867 click to see details on this item	2.7.1.1Name: hexokinase Other names: hexokinase type IV glucokinase, hexokinase D, hexokinase type IV, hexokinase (phosphorylating), ATP-dependent hexokinase, glucose ATP phosphotransferase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + fruName: D-Fructose Formula: C6H12O6 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + f6pName: D-Fructose 6-phosphate Formula: C6H11O9P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hxk-1 \| hxk-2 \| hxk-3	Amino sugar and nucleotide sugar metabolism
RC00875Name: D-sorbitol dehydrogenase Type: Regular Location: Cytosol KEGG ID: R00875 click to see details on this item	1.1.1.14Name: L-iditol 2-dehydrogenase Other names: polyol dehydrogenase, sorbitol dehydrogenase, L-iditol:NAD+ 5-oxidoreductase, L-iditol (sorbitol) dehydrogenase, glucitol dehydrogenase, L-iditol:NAD+ oxidoreductase, NAD+-dependent sorbitol dehydrogenase, NAD+-sorbitol dehydrogenase click to see details on this item	[c] : nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item + sbt-DName: D-Sorbitol Formula: C6H14O6 Charge: 0 click to see details on this item		fruName: D-Fructose Formula: C6H12O6 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	R04B5.5 \| R04B5.6	Fructose and mannose metabolism
RC00801Name: sucrose glucohydrolase Type: Regular Location: Cytosol KEGG ID: R00801 click to see details on this item	3.2.1.20Name: alpha-glucosidase Other names: maltase, glucoinvertase, glucosidosucrase, maltase-glucoamylase, alpha-glucopyranosidase, glucosidoinvertase, alpha-D-glucosidase, alpha-glucoside hydrolase, alpha-1,4-glucosidase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + sucrName: Sucrose Formula: C12H22O11 Charge: 0 click to see details on this item		fruName: D-Fructose Formula: C6H12O6 Charge: 0 click to see details on this item + glc-DName: D-Glucose Formula: C6H12O6 Charge: 0 click to see details on this item	aagr-1 \| aagr-2	Galactose metabolism
TCE0648Name: D-Fructose transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	fruName: D-Fructose Formula: C6H12O6 Charge: 0 click to see details on this item[e]		fruName: D-Fructose Formula: C6H12O6 Charge: 0 click to see details on this item[c]	Not determined	Transport
EX00095Name: D-Fructose exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	fruName: D-Fructose Formula: C6H12O6 Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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