WormFlux: mechanistic analysis of C. elegans metabolism

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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	1.17.4.1
Name .....................................................	:	Ribonucleoside-diphosphate reductase, etc.Ribonucleotide reductase, CDP reductase, Ribonucleoside diphosphate reductase, UDP reductase, ADP reductase, Nucleoside diphosphate reductase, Ribonucleoside 5'-diphosphate reductase, Ribonucleotide diphosphate reductase, 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase, RR
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K00526E1.17.4.1B nrdB nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1], K10807RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1], K10808RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
Genes .....................................................	:	F19G12.2, F58F9.1, rnr-1, rnr-2
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC02017Name: 2-Deoxyadenosine 5-diphosphate:oxidized-thioredoxin 2-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02017 click to see details on this item	1.17.4.1Name: ribonucleoside-diphosphate reductase Other names: ribonucleotide reductase, CDP reductase, ribonucleoside diphosphate reductase, UDP reductase, ADP reductase, nucleoside diphosphate reductase, ribonucleoside 5'-diphosphate reductase, ribonucleotide diphosphate reductase, 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase, RR click to see details on this item	[c] : adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + trdrdName: Reduced thioredoxin Formula: XH2 Charge: 0 click to see details on this item		dadpName: dADP Formula: C10H12N5O9P2 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + trdoxName: Oxidized thioredoxin Formula: X Charge: 0 click to see details on this item	rnr-1 & rnr-2 & (F19G12.2 \| F58F9.1)	Purine metabolism
RC02019Name: 2-Deoxyguanosine 5-diphosphate:oxidized-thioredoxin 2-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02019 click to see details on this item	1.17.4.1Name: ribonucleoside-diphosphate reductase Other names: ribonucleotide reductase, CDP reductase, ribonucleoside diphosphate reductase, UDP reductase, ADP reductase, nucleoside diphosphate reductase, ribonucleoside 5'-diphosphate reductase, ribonucleotide diphosphate reductase, 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase, RR click to see details on this item	[c] : gdpName: GDP Formula: C10H12N5O11P2 Charge: -3 click to see details on this item + trdrdName: Reduced thioredoxin Formula: XH2 Charge: 0 click to see details on this item		dgdpName: dGDP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + trdoxName: Oxidized thioredoxin Formula: X Charge: 0 click to see details on this item	rnr-1 & rnr-2 & (F19G12.2 \| F58F9.1)	Purine metabolism
RC02024Name: 2-Deoxycytidine diphosphate:oxidized-thioredoxin 2-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02024 click to see details on this item	1.17.4.1Name: ribonucleoside-diphosphate reductase Other names: ribonucleotide reductase, CDP reductase, ribonucleoside diphosphate reductase, UDP reductase, ADP reductase, nucleoside diphosphate reductase, ribonucleoside 5'-diphosphate reductase, ribonucleotide diphosphate reductase, 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase, RR click to see details on this item	[c] : cdpName: CDP Formula: C9H12N3O11P2 Charge: -3 click to see details on this item + trdrdName: Reduced thioredoxin Formula: XH2 Charge: 0 click to see details on this item		dcdpName: dCDP Formula: C9H12N3O10P2 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + trdoxName: Oxidized thioredoxin Formula: X Charge: 0 click to see details on this item	rnr-1 & rnr-2 & (F19G12.2 \| F58F9.1)	Pyrimidine metabolism
RC02018Name: 2-Deoxyuridine 5-diphosphate:oxidized-thioredoxin 2-oxidoreductase Type: Regular Location: Cytosol KEGG ID: R02018 click to see details on this item	1.17.4.1Name: ribonucleoside-diphosphate reductase Other names: ribonucleotide reductase, CDP reductase, ribonucleoside diphosphate reductase, UDP reductase, ADP reductase, nucleoside diphosphate reductase, ribonucleoside 5'-diphosphate reductase, ribonucleotide diphosphate reductase, 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase, RR click to see details on this item	[c] : trdrdName: Reduced thioredoxin Formula: XH2 Charge: 0 click to see details on this item + udpName: UDP Formula: C9H11N2O12P2 Charge: -3 click to see details on this item		dudpName: dUDP Formula: C9H11N2O11P2 Charge: -3 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + trdoxName: Oxidized thioredoxin Formula: X Charge: 0 click to see details on this item	rnr-1 & rnr-2 & (F19G12.2 \| F58F9.1)	Pyrimidine metabolism

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