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Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Metabolite Overview
Abbreviation ..................................................... : sphings_ce
Name ..................................................... : Sphingosine
Model ID ..................................................... : CC0211
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : Not available
Formula ..................................................... : C19H40NO2
Charge ..................................................... : +1
Localization ..................................................... : Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : sphings
Other associations ..................................................... : See reaction table below (6 reactions in total)

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Sphingolipid metabolism (c)
Comments
  • Charge based on matching BiGG compound.

    • Reactions
    ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

    I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
    & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

    If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.     		Pathway
    RC01496Name: Acyl-CoA:sphingosine N-acyltransferase
    Type: Regular
    Location: Cytosol
    KEGG ID: R01496

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    2.3.1.24Name: sphingosine N-acyltransferase
    Other names: ceramide synthetase, sphingosine acyltransferase

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    [c] : RtotalcoaName: R total Coenzyme A
    Formula: CO2FULLRC21H31N7O15P3S
    Charge: -4




    click to see details on this item     + sphings_ceName: Sphingosine
    Formula: C19H40NO2
    Charge: 1




    click to see details on this item
    coaName: Coenzyme A
    Formula: C21H32N7O16P3S
    Charge: -4




    click to see details on this item     + crm_ceName: ceramide
    Formula: C19H38NO2FULLRCO
    Charge: 0




    click to see details on this item     + hName: H+
    Formula: H
    Charge: 1




    click to see details on this item
    hyl-1 | hyl-2 | lagr-1
    Sphingolipid metabolism
    RC01494Name: N-Acylsphingosine amidohydrolase
    Type: Regular
    Location: Cytosol
    KEGG ID: R01494

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    3.5.1.23Name: ceramidase
    Other names: acylsphingosine deacylase, glycosphingolipid ceramide deacylase

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    [c] : crm_ceName: ceramide
    Formula: C19H38NO2FULLRCO
    Charge: 0




    click to see details on this item     + h2oName: H2O
    Formula: H2O
    Charge: 0




    click to see details on this item
    RtotalName: R total
    Formula: CO2FULLR
    Charge: -1




    click to see details on this item     + sphings_ceName: Sphingosine
    Formula: C19H40NO2
    Charge: 1




    click to see details on this item
    W02F12.2 | (asah-2 | asah-1)
    Sphingolipid metabolism
    RC01926Name: sphingosine kinase
    Type: Regular
    Location: Cytosol
    KEGG ID: R01926

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    2.7.1.91Name: sphinganine kinase
    Other names: dihydrosphingosine kinase, dihydrosphingosine kinase (phosphorylating), sphingosine kinase (phosphorylating)

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    [c] : atpName: ATP
    Formula: C10H12N5O13P3
    Charge: -4




    click to see details on this item     + sphings_ceName: Sphingosine
    Formula: C19H40NO2
    Charge: 1




    click to see details on this item
    adpName: ADP
    Formula: C10H12N5O10P2
    Charge: -3




    click to see details on this item     + hName: H+
    Formula: H
    Charge: 1




    click to see details on this item     + sphs1p_ceName: Sphingosine 1-phosphate
    Formula: C19H39NO5P
    Charge: -1




    click to see details on this item
    sphk-1
    Sphingolipid metabolism
    RC06521Name: Sphingosine 1-phosphate phosphohydrolase
    Type: Regular
    Location: Cytosol
    KEGG ID: R06521

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    3.1.3.4Name: phosphatidate phosphatase
    Other names: phosphatic acid phosphatase, acid phosphatidyl phosphatase, phosphatic acid phosphohydrolase, PAP, Lipin

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    [c] : h2oName: H2O
    Formula: H2O
    Charge: 0




    click to see details on this item     + sphs1p_ceName: Sphingosine 1-phosphate
    Formula: C19H39NO5P
    Charge: -1




    click to see details on this item
    piName: Phosphate
    Formula: HO4P
    Charge: -2




    click to see details on this item     + sphings_ceName: Sphingosine
    Formula: C19H40NO2
    Charge: 1




    click to see details on this item
    F13E6.5 | F53C3.13 | T28D9.3
    Sphingolipid metabolism
    TCE5399Name: Sphingosine transport
    Type: Transport
    Location: Cytosol, Extracellular
    KEGG ID: NA

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    Not applicable
    sphings_ceName: Sphingosine
    Formula: C19H40NO2
    Charge: 1




    click to see details on this item    [c]
    sphings_ceName: Sphingosine
    Formula: C19H40NO2
    Charge: 1




    click to see details on this item    [e]
    Not determined
    Transport
    EXC0211Name: Sphingosine exchange
    Type: Exchange
    Location: Extracellular
    KEGG ID: NA

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    Not applicable
    sphings_ceName: Sphingosine
    Formula: C19H40NO2
    Charge: 1




    click to see details on this item    [e]
    Not applicable
    Exchange with the environment
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