WormFlux: mechanistic analysis of C. elegans metabolism

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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	3.1.2.4
Name .....................................................	:	3-hydroxyisobutyryl-CoA hydrolase, etc.3-hydroxy-isobutyryl CoA hydrolase, HIB CoA deacylase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K05605HIBCH; 3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4]
Genes .....................................................	:	hach-1
Localization .....................................................	:	Mitochondria, Cytosol
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0134Name: (S) 3-hydroxybutyryl-CoA hydrolase Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	3.1.2.4Name: 3-hydroxyisobutyryl-CoA hydrolase Other names: 3-hydroxy-isobutyryl CoA hydrolase, HIB CoA deacylase click to see details on this item	[c] : 3hbcoaName: (S)-3-Hydroxybutanoyl-CoA Formula: C25H38N7O18P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		S3hbName: (S)-3-Hydroxybutanoate Formula: C4H7O3 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hach-1	Ketone body metabolism
RM03158Name: 3-Hydroxypropionyl-CoA hydrolase Type: Regular Location: Mitochondria KEGG ID: R03158 click to see details on this item	3.1.2.4Name: 3-hydroxyisobutyryl-CoA hydrolase Other names: 3-hydroxy-isobutyryl CoA hydrolase, HIB CoA deacylase click to see details on this item	[m] : 3hpcoaName: 3-Hydroxypropionyl-CoA Formula: C24H36N7O18P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		3hppName: 3-Hydroxypropanoate Formula: C3H5O3 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hach-1	Propionate degradation
RM05064Name: (S)-3-Hydroxyisobutyryl-CoA hydrolase Type: Regular Location: Mitochondria KEGG ID: R05064 click to see details on this item	3.1.2.4Name: 3-hydroxyisobutyryl-CoA hydrolase Other names: 3-hydroxy-isobutyryl CoA hydrolase, HIB CoA deacylase click to see details on this item	[m] : 3hibutcoaName: (S)-3-Hydroxyisobutyryl-CoA Formula: C25H38N7O18P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		3hmpName: 3-Hydroxy-2-methylpropanoate Formula: C4H7O3 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hach-1	Valine degradation

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