Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	3hpcoa
Name .....................................................	:	3-Hydroxypropionyl-CoA, etc.3-Hydroxypropionyl coenzyme A, 3-Hydroxypropanoyl-CoA, 3-Hydroxypropanoyl coenzymeA, beta-Hydroxypropionyl-CoA
Model ID .....................................................	:	C05668
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C05668
Formula .....................................................	:	C24H36N7O18P3S
Charge .....................................................	:	-4
Localization .....................................................	:	Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	3hpcoa
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Propionate degradation (m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM03045Name: 3-Hydroxypropionyl-CoA hydro-lyase Type: Regular Location: Mitochondria KEGG ID: R03045 click to see details on this item	4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item	[m] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + prpncoaName: Propenoyl-CoA Formula: C24H34N7O17P3S Charge: -4 click to see details on this item		3hpcoaName: 3-Hydroxypropionyl-CoA Formula: C24H36N7O18P3S Charge: -4 click to see details on this item	ech-6	Propionate degradation
RM03158Name: 3-Hydroxypropionyl-CoA hydrolase Type: Regular Location: Mitochondria KEGG ID: R03158 click to see details on this item	3.1.2.4Name: 3-hydroxyisobutyryl-CoA hydrolase Other names: 3-hydroxy-isobutyryl CoA hydrolase, HIB CoA deacylase click to see details on this item	[m] : 3hpcoaName: 3-Hydroxypropionyl-CoA Formula: C24H36N7O18P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		3hppName: 3-Hydroxypropanoate Formula: C3H5O3 Charge: -1 click to see details on this item + coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	hach-1	Propionate degradation

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