WormFlux: mechanistic analysis of C. elegans metabolism

HOME DOWNLOAD CITATION HELP

(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	molybd
Name .....................................................	:	Molybdopterin, etc.Pyranopterin, H2Dtpp-mP
Model ID .....................................................	:	C05924
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C05924
Formula .....................................................	:	C10H11N5O6PS2
Charge .....................................................	:	-3
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	Not available
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Alanine metabolism (c), Cysteine metabolism (c), Molybdenum cofactor biosynthesis (c)

iCEL1314

Comments

Charge beased on MetaCyc and 3DMET.

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RCC0142Name: molybdopterin synthesis-merged Type: Regular Location: Cytosol KEGG ID: R07460;R09395 click to see details on this item	2.8.1.7Name: cysteine desulfurase Other names: IscS, NIFS, NifS, SufS, cysteine desulfurylase click to see details on this item 2.7.7.80Name: molybdopterin-synthase adenylyltransferase Other names: MoeB, adenylyltransferase and sulfurtransferase MOCS3 click to see details on this item 2.8.1.11Name: molybdopterin synthase sulfurtransferase Other names: adenylyltransferase and sulfurtransferase MOCS3, Cnx5 (gene name), molybdopterin synthase sulfurylase click to see details on this item 2.8.1.12Name: molybdopterin synthase Other names: MPT synthase click to see details on this item	[c] : cpmpName: Cyclic pyranopterin monophosphate Formula: C10H11N5O7P Charge: -1 click to see details on this item + (2) cys-LName: L-Cysteine Formula: C3H7NO2S Charge: 0 click to see details on this item + (2) trdrdName: Reduced thioredoxin Formula: XH2 Charge: 0 click to see details on this item + (2) atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		molybdName: Molybdopterin Formula: C10H11N5O6PS2 Charge: -3 click to see details on this item + (2) ala-LName: L-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + (2) trdoxName: Oxidized thioredoxin Formula: X Charge: 0 click to see details on this item + (2) ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + (2) ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item + (4) hName: H+ Formula: H Charge: 1 click to see details on this item	B0205.6 & moc-3 & (T27A3.6 & K10D2.7)	Alanine metabolism
RCC0143Name: molybdopterin adenylyl transferase; molybdopterin molybdotransferase Type: Regular Location: Cytosol KEGG ID: R09726;R09735 click to see details on this item	2.7.7.75Name: molybdopterin adenylyltransferase Other names: MogA, Cnx1 (ambiguous) click to see details on this item 2.10.1.1Name: molybdopterin molybdotransferase Other names: MoeA, Cnx1 (ambiguous) click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + molybdName: Molybdopterin Formula: C10H11N5O6PS2 Charge: -3 click to see details on this item + mobdName: Molybdate Formula: MoO4 Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item		mocoName: Adenylated molybdopterin Formula: C10H10N5O8PS2Mo Charge: -2 click to see details on this item + ampName: AMP Formula: C10H12N5O7P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	lin-46 \| moc-1 \| moc-2	Molybdenum cofactor biosynthesis

The information and tools provided in this website are to be used for academic purposes only.