Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	gar
Name .....................................................	:	N1-(5-Phospho-D-ribosyl)glycinamide, etc.5'-Phosphoribosylglycinamide, GAR, Glycinamide ribonucleotide
Model ID .....................................................	:	C03838
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C03838
Formula .....................................................	:	C7H14N2O8P
Charge .....................................................	:	-1
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	gar
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Folate cycle (c), Glycine and threonine metabolism (c), Purine metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC04326Name: 5'-Phosphoribosyl-N-formylglycinamide formation by 5,10-Methenyltetrahydrofolate Type: Regular Location: Cytosol KEGG ID: R04326 click to see details on this item	2.1.2.2Name: phosphoribosylglycinamide formyltransferase Other names: 2-amino-N-ribosylacetamide 5'-phosphate transformylase, GAR formyltransferase, GAR transformylase, glycinamide ribonucleotide transformylase, GAR TFase, 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase click to see details on this item	[c] : garName: N1-(5-Phospho-D-ribosyl)glycinamide Formula: C7H14N2O8P Charge: -1 click to see details on this item + methfName: "5,10-Methenyltetrahydrofolate" Formula: C20H20N7O6 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		fgamName: N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide Formula: C8H13N2O9P Charge: -2 click to see details on this item + thfName: "5,6,7,8-Tetrahydrofolate" Formula: C19H21N7O6 Charge: -2 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item	F38B6.4	Folate cycle
RC04144Name: 5-Phospho-D-ribosylamine:glycine ligase (ADP-forming) Type: Regular Location: Cytosol KEGG ID: R04144 click to see details on this item	6.3.4.13Name: phosphoribosylamine---glycine ligase Other names: phosphoribosylglycinamide synthetase, glycinamide ribonucleotide synthetase, phosphoribosylglycineamide synthetase, glycineamide ribonucleotide synthetase, 2-amino-N-ribosylacetamide 5'-phosphate kinosynthase, 5'-phosphoribosylglycinamide synthetase, GAR click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + glyName: Glycine Formula: C2H5NO2 Charge: 0 click to see details on this item + pramName: 5-Phospho-beta-D-ribosylamine Formula: C5H11NO7P Charge: -1 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + garName: N1-(5-Phospho-D-ribosyl)glycinamide Formula: C7H14N2O8P Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F38B6.4	Glycine and threonine metabolism
RC04325Name: 10-Formyltetrahydrofolate:5-phosphoribosylglycinamide formyltransferase Type: Regular Location: Cytosol KEGG ID: R04325 click to see details on this item	2.1.2.2Name: phosphoribosylglycinamide formyltransferase Other names: 2-amino-N-ribosylacetamide 5'-phosphate transformylase, GAR formyltransferase, GAR transformylase, glycinamide ribonucleotide transformylase, GAR TFase, 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase click to see details on this item	[c] : 10fthfName: 10-Formyltetrahydrofolate Formula: C20H21N7O7 Charge: -2 click to see details on this item + garName: N1-(5-Phospho-D-ribosyl)glycinamide Formula: C7H14N2O8P Charge: -1 click to see details on this item		fgamName: N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide Formula: C8H13N2O9P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + thfName: "5,6,7,8-Tetrahydrofolate" Formula: C19H21N7O6 Charge: -2 click to see details on this item	F38B6.4	Folate cycle

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