WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	ascb-L
Name .....................................................	:	L-Ascorbate, etc.Ascorbate, Ascorbic acid, L-Ascorbic acid, Vitamin C
Model ID .....................................................	:	C00072
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00072
Formula .....................................................	:	C6H8O6
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	ascb-L
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Glutathione metabolism (c), Tyrosine metabolism (c)

iCEL1314

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ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01108Name: glutathione dehydrogenase (ascorbate) Type: Regular Location: Cytosol KEGG ID: R01108 click to see details on this item	1.8.5.1Name: glutathione dehydrogenase (ascorbate) Other names: dehydroascorbic reductase, dehydroascorbic acid reductase, glutathione dehydroascorbate reductase, DHA reductase , dehydroascorbate reductase, GDOR, glutathione:dehydroascorbic acid oxidoreductase click to see details on this item	[c] : dhdascbName: Dehydroascorbate Formula: C6H6O6 Charge: 0 click to see details on this item + (2) gthrdName: Reduced glutathione Formula: C10H16N3O6S Charge: -1 click to see details on this item		ascb-LName: L-Ascorbate Formula: C6H8O6 Charge: 0 click to see details on this item + gthoxName: Oxidized glutathione Formula: C20H30N6O12S2 Charge: -2 click to see details on this item	Unknown	Glutathione metabolism
RCC0156Name: tyramine beta-monooxygenase Type: Regular Location: Cytosol KEGG ID: NA click to see details on this item	1.14.17.-Name: tyramine beta-monooxygenase click to see details on this item	[c] : tymName: Tyramine Formula: C8H12NO Charge: 1 click to see details on this item + ascb-LName: L-Ascorbate Formula: C6H8O6 Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		octpmnName: Octopamine Formula: C8H12NO2 Charge: 1 click to see details on this item + dhdascbName: Dehydroascorbate Formula: C6H6O6 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	tbh-1	Tyrosine metabolism
DMN0038Name: vitamin C demand Type: Demand Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	ascb-LName: L-Ascorbate Formula: C6H8O6 Charge: 0 click to see details on this item[c]			Not applicable	Demand reactions
TCE0694Name: L-Ascorbate transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	ascb-LName: L-Ascorbate Formula: C6H8O6 Charge: 0 click to see details on this item[e]		ascb-LName: L-Ascorbate Formula: C6H8O6 Charge: 0 click to see details on this item[c]	Not determined	Transport
EX00072Name: L-Ascorbate exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	ascb-LName: L-Ascorbate Formula: C6H8O6 Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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