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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 6.3.2.2
Name ..................................................... : Glutamate---cysteine ligase, etc.Gamma-glutamylcysteine synthetase, Gamma-glutamyl-L-cysteine synthetase, Gamma-glutamylcysteinyl synthetase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K11204GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
Genes ..................................................... : gcs-1
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC00894Name: L-glutamate:L-cysteine gamma-ligase (ADP-forming)
Type: Regular
Location: Cytosol
KEGG ID: R00894

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6.3.2.2Name: glutamate---cysteine ligase
Other names: gamma-glutamylcysteine synthetase, gamma-glutamyl-L-cysteine synthetase, gamma-glutamylcysteinyl synthetase

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[c] : atpName: ATP
Formula: C10H12N5O13P3
Charge: -4




click to see details on this item + cys-LName: L-Cysteine
Formula: C3H7NO2S
Charge: 0




click to see details on this item + glu-LName: L-Glutamate
Formula: C5H8NO4
Charge: -1




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adpName: ADP
Formula: C10H12N5O10P2
Charge: -3




click to see details on this item + glucysName: gamma-L-Glutamyl-L-cysteine
Formula: C8H13N2O5S
Charge: -1




click to see details on this item + hName: H+
Formula: H
Charge: 1




click to see details on this item + piName: Phosphate
Formula: HO4P
Charge: -2




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gcs-1 | E01A2.1
Cysteine metabolism
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