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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 4.1.3.4
Name ..................................................... : Hydroxymethylglutaryl-CoA lyase, etc.Hydroxymethylglutaryl coenzyme A-cleaving enzyme, Hydroxymethylglutaryl coenzyme A lyase, 3-hydroxy-3-methylglutaryl coenzyme A lyase, 3-hydroxy-3-methylglutaryl CoA cleaving enzyme, 3-hydroxy-3-methylglutaryl-CoA lyase, (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K01640E4.1.3.4 HMGCL hmgL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
Genes ..................................................... : Y71G12B.10
Localization ..................................................... : Mitochondria
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RM01360Name: (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)
Type: Regular
Location: Mitochondria
KEGG ID: R01360

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4.1.3.4Name: hydroxymethylglutaryl-CoA lyase
Other names: hydroxymethylglutaryl coenzyme A-cleaving enzyme, hydroxymethylglutaryl coenzyme A lyase, 3-hydroxy-3-methylglutaryl coenzyme A lyase, 3-hydroxy-3-methylglutaryl CoA cleaving enzyme, 3-hydroxy-3-methylglutaryl-CoA lyase, (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase

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[m] : hmgcoaName: Hydroxymethylglutaryl-CoA
Formula: C27H39N7O20P3S
Charge: -5




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acacName: Acetoacetate
Formula: C4H5O3
Charge: -1




click to see details on this item + accoaName: Acetyl-CoA
Formula: C23H34N7O17P3S
Charge: -4




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Y71G12B.10
Ketone body metabolism
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