WormFlux: mechanistic analysis of C. elegans metabolism

HOME DOWNLOAD CITATION HELP

(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	2.6.1.5
Name .....................................................	:	Tyrosine transaminase, etc.Tyrosine aminotransferase, Glutamic-hydroxyphenylpyruvic transaminase, Glutamic phenylpyruvic aminotransferase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, Phenylalanine aminotransferase, Phenylalanine transaminase, Phenylalanine-alpha-ketoglutarate transaminase, Phenylpyruvate transaminase, Phenylpyruvic acid transaminase, Tyrosine-alpha-ketoglutarate aminotransferase, Tyrosine-alpha-ketoglutarate transaminase, Tyrosine-2-ketoglutarate aminotransferase, TyrAT
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K00815TAT; tyrosine aminotransferase [EC:2.6.1.5]
Genes .....................................................	:	tatn-1
Localization .....................................................	:	Cytosol, Mitochondria
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC07396Name: 2-keto-4-methylthiobutyrate transamination Type: Regular Location: Cytosol KEGG ID: R07396 click to see details on this item	2.6.1.5Name: tyrosine transaminase Other names: tyrosine aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, glutamic phenylpyruvic aminotransferase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, tyrosine-2-ketoglutarate aminotransferase, TyrAT click to see details on this item	[c] : 2kmbName: 2-keto-4-methylthiobutyrate Formula: C5H7O3S Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item		akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + met-LName: L-Methionine Formula: C5H11NO2S Charge: 0 click to see details on this item	tatn-1	Methionine salvage
RC00694Name: L-Phenylalanine:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R00694 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item 2.6.1.5Name: tyrosine transaminase Other names: tyrosine aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, glutamic phenylpyruvic aminotransferase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, tyrosine-2-ketoglutarate aminotransferase, TyrAT click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + phe-LName: L-Phenylalanine Formula: C9H11NO2 Charge: 0 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + phpyrName: Phenylpyruvate Formula: C9H7O3 Charge: -1 click to see details on this item	got-1.2 \| tatn-1	Phenylalanine degradation
RM00734Name: L-tyrosine:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R00734 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item 2.6.1.5Name: tyrosine transaminase Other names: tyrosine aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, glutamic phenylpyruvic aminotransferase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, tyrosine-2-ketoglutarate aminotransferase, TyrAT click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + tyr-LName: L-Tyrosine Formula: C9H11NO3 Charge: 0 click to see details on this item		34hppName: 3-(4-Hydroxyphenyl)pyruvate Formula: C9H7O4 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-2.1 \| got-2.2	Tyrosine metabolism
RC00734Name: L-tyrosine:2-oxoglutarate aminotransferase Type: Regular Location: Cytosol KEGG ID: R00734 click to see details on this item	2.6.1.1Name: aspartate transaminase Other names: glutamic-oxaloacetic transaminase, glutamic-aspartic transaminase, transaminase A, AAT, AspT, 2-oxoglutarate-glutamate aminotransferase, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AST, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamic-aspartic aminotransferase, glutamic-oxalacetic transaminase, glutamic oxalic transaminase, GOT (enzyme) [ambiguous], L-aspartate transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartic aminotransferase, oxaloacetate-aspartate aminotransferase, oxaloacetate transferase, aspartate:2-oxoglutarate aminotransferase, glutamate oxaloacetate transaminase click to see details on this item 2.6.1.5Name: tyrosine transaminase Other names: tyrosine aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, glutamic phenylpyruvic aminotransferase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, tyrosine-2-ketoglutarate aminotransferase, TyrAT click to see details on this item	[c] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + tyr-LName: L-Tyrosine Formula: C9H11NO3 Charge: 0 click to see details on this item		34hppName: 3-(4-Hydroxyphenyl)pyruvate Formula: C9H7O4 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item	got-1.2 \| tatn-1	Tyrosine metabolism

The information and tools provided in this website are to be used for academic purposes only.