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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 2.3.3.8
Name ..................................................... : ATP citrate synthase, etc.ATP-citric lyase, ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-->acetyl-CoA] (ATP-dephosphorylating), Acetyl-CoA:oxaloacetate acetyltransferase (isomerizing, ADP-phosphorylating), Adenosine triphosphate citrate lyase, Citrate cleavage enzyme, Citrate-ATP lyase, Citric cleavage enzyme, ATP citrate (pro-S)-lyase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K01648ACLY; ATP citrate (pro-S)-lyase [EC:2.3.3.8]
Genes ..................................................... : acly-1, acly-2
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC00352Name: acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]
Type: Regular
Location: Cytosol
KEGG ID: R00352

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2.3.3.8Name: ATP citrate synthase
Other names: ATP-citric lyase, ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-->acetyl-CoA] (ATP-dephosphorylating), acetyl-CoA:oxaloacetate acetyltransferase (isomerizing, ADP-phosphorylating), adenosine triphosphate citrate lyase, citrate cleavage enzyme, citrate-ATP lyase, citric cleavage enzyme, ATP citrate (pro-S)-lyase

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[c] : atpName: ATP
Formula: C10H12N5O13P3
Charge: -4




click to see details on this item + citName: Citrate
Formula: C6H5O7
Charge: -3




click to see details on this item + coaName: Coenzyme A
Formula: C21H32N7O16P3S
Charge: -4




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adpName: ADP
Formula: C10H12N5O10P2
Charge: -3




click to see details on this item + piName: Phosphate
Formula: HO4P
Charge: -2




click to see details on this item + accoaName: Acetyl-CoA
Formula: C23H34N7O17P3S
Charge: -4




click to see details on this item + oaaName: Oxaloacetate
Formula: C4H2O5
Charge: -2




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acly-2 | acly-1
TCA cycle
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