HOME DOWNLOAD CITATION HELP
Umass Logo PSB Logo
(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 2.1.1.45
Name ..................................................... : Thymidylate synthase, etc.DTMP synthase, Thymidylate synthetase, Methylenetetrahydrofolate:dUMP C-methyltransferase, TMP synthetase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K00560thyA TYMS; thymidylate synthase [EC:2.1.1.45]
Genes ..................................................... : tyms-1
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC02101Name: 5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase
Type: Regular
Location: Cytosol
KEGG ID: R02101

click to see details on this item
2.1.1.45Name: thymidylate synthase
Other names: dTMP synthase, thymidylate synthetase, methylenetetrahydrofolate:dUMP C-methyltransferase, TMP synthetase

click to see details on this item
[c] : dumpName: dUMP
Formula: C9H11N2O8P
Charge: -2




click to see details on this item + mlthfName: "5,10-Methylenetetrahydrofolate"
Formula: C20H21N7O6
Charge: -2




click to see details on this item
dhfName: "7,8-Dihydrofolate"
Formula: C19H19N7O6
Charge: -2




click to see details on this item + dtmpName: dTMP
Formula: C10H13N2O8P
Charge: -2




click to see details on this item
tyms-1
Folate cycle
The information and tools provided in this website are to be used for academic purposes only.