WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
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Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	aicar
Name .....................................................	:	5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide, etc.1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide, 5'-Phosphoribosyl-5-amino-4-imidazolecarboxamide, 5'-Phospho-ribosyl-5-amino-4-imidazole carboxamide, AICAR, 5-Aminoimidazole-4-carboxamide ribotide, 5-Phosphoribosyl-4-carbamoyl-5-aminoimidazole
Model ID .....................................................	:	C04677
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C04677
Formula .....................................................	:	C9H13N4O8P
Charge .....................................................	:	-2
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	aicar
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Folate cycle (c), Purine metabolism (c)

iCEL1314

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Enzyme

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Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC04559Name: 1-(5-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase Type: Regular Location: Cytosol KEGG ID: R04559 click to see details on this item	4.3.2.2Name: adenylosuccinate lyase Other names: adenylosuccinase, succino AMP-lyase, 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase, 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) click to see details on this item	[c] : 25aicsName: (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate Formula: C13H15N4O12P Charge: -4 click to see details on this item		aicarName: 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide Formula: C9H13N4O8P Charge: -2 click to see details on this item + fumName: Fumarate Formula: C4H2O4 Charge: -2 click to see details on this item	adsl-1	Purine metabolism
RC04560Name: 10-Formyltetrahydrofolate:5-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase Type: Regular Location: Cytosol KEGG ID: R04560 click to see details on this item	2.1.2.3Name: phosphoribosylaminoimidazolecarboxamide formyltransferase Other names: 5-amino-4-imidazolecarboxamide ribonucleotide transformylase, AICAR transformylase, 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase, 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase, 5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase, 5-amino-4-imidazolecarboxamide ribotide transformylase, AICAR formyltransferase, aminoimidazolecarboxamide ribonucleotide transformylase click to see details on this item	[c] : 10fthfName: 10-Formyltetrahydrofolate Formula: C20H21N7O7 Charge: -2 click to see details on this item + aicarName: 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide Formula: C9H13N4O8P Charge: -2 click to see details on this item		fpricaName: 5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide Formula: C10H13N4O9P Charge: -2 click to see details on this item + thfName: "5,6,7,8-Tetrahydrofolate" Formula: C19H21N7O6 Charge: -2 click to see details on this item	atic-1	Folate cycle
TCE5316Name: 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	aicarName: 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide Formula: C9H13N4O8P Charge: -2 click to see details on this item[e]		aicarName: 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide Formula: C9H13N4O8P Charge: -2 click to see details on this item[c]	Not determined	Transport
EX04677Name: 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	aicarName: 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide Formula: C9H13N4O8P Charge: -2 click to see details on this item[e]			Not applicable	Exchange with the environment

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