WormFlux: mechanistic analysis of C. elegans metabolism

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PEAPathway Enrichment Analysis

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Metabolite Overview

Abbreviation .....................................................	:	fprica
Name .....................................................	:	5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, etc.1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide, 5'-Phosphoribosyl-5-formamido-4-imidazolecarboxamide, 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide, FAICAR
Model ID .....................................................	:	C04734
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C04734
Formula .....................................................	:	C10H13N4O9P
Charge .....................................................	:	-2
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	fprica
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Folate cycle (c), Purine metabolism (c)

iCEL1314

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Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC04560Name: 10-Formyltetrahydrofolate:5-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase Type: Regular Location: Cytosol KEGG ID: R04560 click to see details on this item	2.1.2.3Name: phosphoribosylaminoimidazolecarboxamide formyltransferase Other names: 5-amino-4-imidazolecarboxamide ribonucleotide transformylase, AICAR transformylase, 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase, 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase, 5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase, 5-amino-4-imidazolecarboxamide ribotide transformylase, AICAR formyltransferase, aminoimidazolecarboxamide ribonucleotide transformylase click to see details on this item	[c] : 10fthfName: 10-Formyltetrahydrofolate Formula: C20H21N7O7 Charge: -2 click to see details on this item + aicarName: 5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide Formula: C9H13N4O8P Charge: -2 click to see details on this item		fpricaName: 5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide Formula: C10H13N4O9P Charge: -2 click to see details on this item + thfName: "5,6,7,8-Tetrahydrofolate" Formula: C19H21N7O6 Charge: -2 click to see details on this item	atic-1	Folate cycle
RC01127Name: IMP 1,2-hydrolase (decyclizing) Type: Regular Location: Cytosol KEGG ID: R01127 click to see details on this item	2.1.2.3Name: phosphoribosylaminoimidazolecarboxamide formyltransferase Other names: 5-amino-4-imidazolecarboxamide ribonucleotide transformylase, AICAR transformylase, 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase, 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase, 5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase, 5-amino-4-imidazolecarboxamide ribotide transformylase, AICAR formyltransferase, aminoimidazolecarboxamide ribonucleotide transformylase click to see details on this item 3.5.4.10Name: IMP cyclohydrolase Other names: inosinicase, inosinate cyclohydrolase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + impName: IMP Formula: C10H11N4O8P Charge: -2 click to see details on this item		fpricaName: 5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide Formula: C10H13N4O9P Charge: -2 click to see details on this item	atic-1	Purine metabolism

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