HOME DOWNLOAD CITATION HELP
Umass Logo PSB Logo
(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Metabolite Overview
Abbreviation ..................................................... : tmlys
Name ..................................................... : N6,N6,N6-Trimethyl-L-lysine
Model ID ..................................................... : C03793
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : C03793
Formula ..................................................... : C9H21N2O2
Charge ..................................................... : +1
Localization ..................................................... : Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : tmlys
Other associations ..................................................... : See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Not yet represented in WormPaths maps.
Comments
  • Formula and charge based on MetaCyc.

    • Reactions
    ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

    I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
    & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

    If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.     		Pathway
    RC04313Name: Protein lysine peptidase
    Type: Regular
    Location: Cytosol
    KEGG ID: R04313

    click to see details on this item
    3.4.-.-Name: bacterial peptide degradation
    Other names: protein lysine peptidase

    click to see details on this item
    [c] : peptmelysName: Protein N6,N6,N6-trimethyl-L-lysine
    Formula: XC9H19N2O
    Charge: 1




    click to see details on this item     + h2oName: H2O
    Formula: H2O
    Charge: 0




    click to see details on this item
    pepXName: Random peptide (special aminoacid carrier)
    Formula: X
    Charge: 0




    click to see details on this item     + tmlysName: N6,N6,N6-Trimethyl-L-lysine
    Formula: C9H21N2O2
    Charge: 1




    click to see details on this item
    Unknown
    Carnitine biosynthesis
    RM03451Name: trimethyllysine dioxygenase
    Type: Regular
    Location: Mitochondria
    KEGG ID: R03451

    click to see details on this item
    1.14.11.8Name: trimethyllysine dioxygenase
    Other names: trimethyllysine alpha-ketoglutarate dioxygenase, TML-alpha-ketoglutarate dioxygenase, TML hydroxylase, 6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)

    click to see details on this item
    [m] : akgName: 2-Oxoglutarate
    Formula: C5H4O5
    Charge: -2




    click to see details on this item     + o2Name: O2
    Formula: O2
    Charge: 0




    click to see details on this item     + tmlysName: N6,N6,N6-Trimethyl-L-lysine
    Formula: C9H21N2O2
    Charge: 1




    click to see details on this item
    3htmelysName: 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
    Formula: C9H21N2O3
    Charge: 1




    click to see details on this item     + co2Name: CO2
    Formula: CO2
    Charge: 0




    click to see details on this item     + succName: Succinate
    Formula: C4H4O4
    Charge: -2




    click to see details on this item
    gbh-2
    Carnitine biosynthesis
    TCM5064Name: Trimethyl lysine transport to mitochondria
    Type: Transport
    Location: Cytosol, Mitochondria
    KEGG ID: NA

    click to see details on this item
    Not applicable
    tmlysName: N6,N6,N6-Trimethyl-L-lysine
    Formula: C9H21N2O2
    Charge: 1




    click to see details on this item    [c]
    tmlysName: N6,N6,N6-Trimethyl-L-lysine
    Formula: C9H21N2O2
    Charge: 1




    click to see details on this item    [m]
    To be determined
    Transport
    TCE5328Name: N6,N6,N6-Trimethyl-L-lysine transport
    Type: Transport
    Location: Cytosol, Extracellular
    KEGG ID: NA

    click to see details on this item
    Not applicable
    tmlysName: N6,N6,N6-Trimethyl-L-lysine
    Formula: C9H21N2O2
    Charge: 1




    click to see details on this item    [c]
    tmlysName: N6,N6,N6-Trimethyl-L-lysine
    Formula: C9H21N2O2
    Charge: 1




    click to see details on this item    [e]
    Not determined
    Transport
    EX03793Name: N6,N6,N6-Trimethyl-L-lysine exchange
    Type: Exchange
    Location: Extracellular
    KEGG ID: NA

    click to see details on this item
    Not applicable
    tmlysName: N6,N6,N6-Trimethyl-L-lysine
    Formula: C9H21N2O2
    Charge: 1




    click to see details on this item    [e]
    Not applicable
    Exchange with the environment
    The information and tools provided in this website are to be used for academic purposes only.