WormFlux: mechanistic analysis of C. elegans metabolism

HOME DOWNLOAD CITATION HELP

(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	cyanala
Name .....................................................	:	Beta cyanoalanine, etc.3-Cyano-L-alanine, L-3-Cyanoalanine, L-beta-Cyanoalanine
Model ID .....................................................	:	C02512
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C02512
Formula .....................................................	:	C4H5N2O2
Charge .....................................................	:	-1
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	Not available
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Sulfur metabolism (c,e,m)

iCEL1314

Comments

Charge based on MetaCyc.

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC03970Name: (5-Glutamyl)-peptide:amino-acid 5-glutamyltransferase Type: Regular Location: Cytosol KEGG ID: R03970 click to see details on this item	2.3.2.2Name: gamma-glutamyltransferase Other names: glutamyl transpeptidase, alpha-glutamyl transpeptidase, gamma-glutamyl peptidyltransferase, gamma-glutamyl transpeptidase (ambiguous), gamma-GPT, gamma-GT, gamma-GTP, L-gamma-glutamyl transpeptidase, L-gamma-glutamyltransferase, L-glutamyltransferase, GGT (ambiguous), gamma-glutamyltranspeptidase (ambiguous) click to see details on this item	[c] : cyanalaName: Beta cyanoalanine Formula: C4H5N2O2 Charge: -1 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		gcynalaName: gamma-Glutamyl-beta-cyanoalanine Formula: C9H12N3O5 Charge: -1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	C53D5.5 \| H14N18.4 \| T03D8.6 \| T19H12.6 \| Y7A9A.1 \| Y97E10AR.2	Miscellaneous
RM03524Name: L-cysteine hydrogen-sulfide-lyase (adding HCN) Type: Regular Location: Mitochondria KEGG ID: R03524 click to see details on this item	4.4.1.9Name: L-3-cyanoalanine synthase Other names: beta-cyanoalanine synthase, beta-cyanoalanine synthetase, beta-cyano-L-alanine synthase, L-cysteine hydrogen-sulfide-lyase (adding HCN) click to see details on this item	[m] : cys-LName: L-Cysteine Formula: C3H7NO2S Charge: 0 click to see details on this item + cyanName: Hydrogen cyanide Formula: CHN Charge: 0 click to see details on this item		h2sName: Hydrogen sulfide Formula: H2S Charge: 0 click to see details on this item + cyanalaName: Beta cyanoalanine Formula: C4H5N2O2 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	cysl-2	Sulfur metabolism
TCE5007Name: beta cyanoalanine transport to and from cytosol Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	cyanalaName: Beta cyanoalanine Formula: C4H5N2O2 Charge: -1 click to see details on this item[e]		cyanalaName: Beta cyanoalanine Formula: C4H5N2O2 Charge: -1 click to see details on this item[c]	Not determined	Transport
TCM5007Name: beta cyanoalanine transport to and from mitochondrion Type: Transport Location: Cytosol, Mitochondria KEGG ID: NA click to see details on this item	Not applicable	cyanalaName: Beta cyanoalanine Formula: C4H5N2O2 Charge: -1 click to see details on this item[m]		cyanalaName: Beta cyanoalanine Formula: C4H5N2O2 Charge: -1 click to see details on this item[c]	Not determined	Transport
EX02512Name: beta cyanoalanine exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	cyanalaName: Beta cyanoalanine Formula: C4H5N2O2 Charge: -1 click to see details on this item[e]			Not applicable	Exchange with the environment

The information and tools provided in this website are to be used for academic purposes only.