Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	glu5sa
Name .....................................................	:	L-Glutamate 5-semialdehyde, etc.L-Glutamate gamma-semialdehyde
Model ID .....................................................	:	C01165
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C01165
Formula .....................................................	:	C5H9NO3
Charge .....................................................	:	0
Localization .....................................................	:	Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	glu5sa
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Arginine metabolism (m), Proline metabolism (m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM00667Name: L-Ornithine:2-oxo-acid aminotransferase Type: Regular Location: Mitochondria KEGG ID: R00667 click to see details on this item	2.6.1.13Name: ornithine aminotransferase Other names: ornithine delta-transaminase, L-ornithine:alpha-ketoglutarate delta-aminotransferase, OAT, L-ornithine 5-aminotransferase, L-ornithine aminotransferase, ornithine 5-aminotransferase, ornithine transaminase, ornithine-alpha-ketoglutarate aminotransferase, ornithine-2-oxoacid aminotransferase, ornithine-keto acid aminotransferase, ornithine-keto acid transaminase, ornithine-ketoglutarate aminotransferase, ornithine-oxo acid aminotransferase, ornithine:alpha-oxoglutarate transaminase, ornithine---oxo-acid transaminase click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + ornName: Ornithine Formula: C5H13N2O2 Charge: 1 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + glu5saName: L-Glutamate 5-semialdehyde Formula: C5H9NO3 Charge: 0 click to see details on this item	oatr-1	Arginine metabolism
RMC0015Name: L-glutamate 5-semialdehyde dehydratase, mitochondrial Type: Regular Location: Mitochondria KEGG ID: NA click to see details on this item	spontaneous	[m] : glu5saName: L-Glutamate 5-semialdehyde Formula: C5H9NO3 Charge: 0 click to see details on this item		1pyr5cName: 1-Pyrroline-5-carboxylate Formula: C5H6NO2 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	Not applicable	Arginine metabolism
RM00245Name: L-Glutamate 5-semialdehyde:NAD+ oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R00245 click to see details on this item	1.2.1.88Name: L-glutamate gamma-semialdehyde dehydrogenase Other names: 1-pyrroline-5-carboxylate dehydrogenase, Delta1-pyrroline-5-carboxylate dehydrogenase, 1-pyrroline dehydrogenase, pyrroline-5-carboxylate dehydrogenase, pyrroline-5-carboxylic acid dehydrogenase, L-pyrroline-5-carboxylate-NAD+ oxidoreductase, 1-pyrroline-5-carboxylate:NAD+ oxidoreductase, Delta1-pyrroline-5-carboxylic acid dehydrogenase click to see details on this item	[m] : glu5saName: L-Glutamate 5-semialdehyde Formula: C5H9NO3 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item	alh-6	Arginine metabolism
RM03313Name: L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating) Type: Regular Location: Mitochondria KEGG ID: R03313 click to see details on this item	1.2.1.41Name: glutamate-5-semialdehyde dehydrogenase Other names: beta-glutamylphosphate reductase, gamma-glutamyl phosphate reductase, beta-glutamylphosphate reductase, glutamate semialdehyde dehydrogenase, glutamate-gamma-semialdehyde dehydrogenase click to see details on this item	[m] : glu5pName: L-Glutamate 5-phosphate Formula: C5H8NO7P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		glu5saName: L-Glutamate 5-semialdehyde Formula: C5H9NO3 Charge: 0 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	alh-13	Arginine metabolism

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