Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	b2coa
Name .....................................................	:	Crotonoyl-CoA, etc.Crotonyl-CoA, 2-Butenoyl-CoA, trans-But-2-enoyl-CoA, But-2-enoyl-CoA, (E)-But-2-enoyl-CoA
Model ID .....................................................	:	C00877
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00877
Formula .....................................................	:	C25H36N7O17P3S
Charge .....................................................	:	-4
Localization .....................................................	:	Mitochondria
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	b2coa
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Ketone body metabolism (m), Lysine degradation (m), Mitochondrial fatty acid degradation (m)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RM03026Name: (S)-3-Hydroxybutanoyl-CoA hydro-lyase Type: Regular Location: Mitochondria KEGG ID: R03026 click to see details on this item	4.2.1.17Name: enoyl-CoA hydratase Other names: enoyl hydrase, unsaturated acyl-CoA hydratase, beta-hydroxyacyl-CoA dehydrase, beta-hydroxyacid dehydrase, hydratase, enoyl coenzyme A, acyl coenzyme A hydrase, crotonase, crotonyl hydrase, 2-octenoyl coenzyme A hydrase, enoyl coenzyme A hydratase, 2-enoyl-CoA hydratase, short-chain enoyl-CoA hydratase, ECH, trans-2-enoyl-CoA hydratase, enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), short chain enoyl coenzyme A hydratase, D-3-hydroxyacyl-CoA dehydratase, enol-CoA hydratase click to see details on this item	[m] : 3hbcoaName: (S)-3-Hydroxybutanoyl-CoA Formula: C25H38N7O18P3S Charge: -4 click to see details on this item		b2coaName: Crotonoyl-CoA Formula: C25H36N7O17P3S Charge: -4 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item	(ech-6 | ech-7) | (ech-1.2 | ech-1.1) | ech-3	Ketone body metabolism
RM01175Name: Butanoyl-CoA:oxygen 2-oxidoreductase Type: Regular Location: Mitochondria KEGG ID: R01175 click to see details on this item	1.3.8.7Name: medium-chain acyl-CoA dehydrogenase Other names: fatty acyl coenzyme A dehydrogenase (ambiguous), acyl coenzyme A dehydrogenase (ambiguous), acyl dehydrogenase (ambiguous), fatty-acyl-CoA dehydrogenase (ambiguous), acyl CoA dehydrogenase (ambiguous), general acyl CoA dehydrogenase (ambiguous), medium-chain acyl-coenzyme A dehydrogenase, acyl-CoA:(acceptor) 2,3-oxidoreductase (ambiguous), ACADM (gene name). click to see details on this item 1.3.8.1Name: short-chain acyl-CoA dehydrogenase Other names: butyryl-CoA dehydrogenase, butanoyl-CoA dehydrogenase, butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, 3-hydroxyacyl CoA reductase, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, ACADS (gene name). click to see details on this item	[m] : btcoaName: Butanoyl-CoA Formula: C25H38N7O17P3S Charge: -4 click to see details on this item + etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item		b2coaName: Crotonoyl-CoA Formula: C25H36N7O17P3S Charge: -4 click to see details on this item + etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item	(acdh-7 | acdh-8 | acdh-10) | (acdh-1 | acdh-2)	Mitochondrial fatty acid degradation
RM02488Name: Glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating) Type: Regular Location: Mitochondria KEGG ID: R02488 click to see details on this item	1.3.8.6Name: glutaryl-CoA dehydrogenase (ETF) Other names: glutaryl coenzyme A dehydrogenase, glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating), glutaryl-CoA dehydrogenase click to see details on this item	[m] : etfoxName: Electron transfer flavoprotein oxidized Formula: R Charge: 0 click to see details on this item + glutcoaName: Glutaryl-CoA Formula: C26H37N7O19P3S Charge: -5 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		b2coaName: Crotonoyl-CoA Formula: C25H36N7O17P3S Charge: -4 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + etfrdName: Electron transfer flavoprotein reduced Formula: RH2 Charge: 0 click to see details on this item	F54D5.7	Lysine degradation

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