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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Metabolite Overview
Abbreviation ..................................................... : srtn
Name ..................................................... : Serotonin, etc.3-(2-Aminoethyl)-1H-indol-5-ol, 5-Hydroxytryptamine, Enteramine
Model ID ..................................................... : C00780
KEGG ID (?) Compounds in KEGG database that match this compound. ..................................................... : C00780
Formula ..................................................... : C10H13N2O
Charge ..................................................... : +1
Localization ..................................................... : Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. ..................................................... : srtn
Other associations ..................................................... : See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here.

Letters after map name indicate the compartments the metabolite is placed in the map:

(c) Cytosol
(m) Mitochondria
(e) Extracellular space ..................................................... 		: Tryptophan degradation (c)
Comments
ERROR
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC02908Name: 5-Hydroxytryptamine:oxygen oxidoreductase (deaminating) (flavin-containing)
Type: Regular
Location: Cytosol
KEGG ID: R02908

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1.4.3.4Name: monoamine oxidase
Other names: adrenalin oxidase, adrenaline oxidase, amine oxidase (ambiguous), amine oxidase (flavin-containing), amine:oxygen oxidoreductase (deaminating) (flavin-containing), epinephrine oxidase, MAO, MAO A, MAO B, MAO-A, MAO-B, monoamine oxidase A, monoamine oxidase B, monoamine:O2 oxidoreductase (deaminating), polyamine oxidase (ambiguous), serotonin deaminase, spermidine oxidase (ambiguous), spermine oxidase (ambiguous), tyraminase, tyramine oxidase

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[c] : srtnName: Serotonin
Formula: C10H13N2O
Charge: 1




click to see details on this item + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + o2Name: O2
Formula: O2
Charge: 0




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5hoxindactName: 5-Hydroxyindoleacetaldehyde
Formula: C10H9NO2
Charge: 0




click to see details on this item + nh4Name: Ammonium
Formula: H4N
Charge: 1




click to see details on this item + h2o2Name: Hydrogen peroxide
Formula: H2O2
Charge: 0




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amx-2
Tryptophan degradation
RC02701Name: 5-Hydroxy-L-tryptophan decarboxy-lyase
Type: Regular
Location: Cytosol
KEGG ID: R02701

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4.1.1.28Name: aromatic-L-amino-acid decarboxylase
Other names: DOPA decarboxylase, tryptophan decarboxylase, hydroxytryptophan decarboxylase, L-DOPA decarboxylase, aromatic amino acid decarboxylase, 5-hydroxytryptophan decarboxylase, aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)

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[c] : 5htrpName: 5-Hydroxy-L-tryptophan
Formula: C11H12N2O3
Charge: 0




click to see details on this item + hName: H+
Formula: H
Charge: 1




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srtnName: Serotonin
Formula: C10H13N2O
Charge: 1




click to see details on this item + co2Name: CO2
Formula: CO2
Charge: 0




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bas-1
Tryptophan degradation
TCE5113Name: Secretion of serotonin
Type: Transport
Location: Cytosol, Extracellular
KEGG ID: NA

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Not applicable
srtnName: Serotonin
Formula: C10H13N2O
Charge: 1




click to see details on this item[c] + atpName: ATP
Formula: C10H12N5O13P3
Charge: -4




click to see details on this item[c] + h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item[c]
srtnName: Serotonin
Formula: C10H13N2O
Charge: 1




click to see details on this item[e] + adpName: ADP
Formula: C10H12N5O10P2
Charge: -3




click to see details on this item[c] + hName: H+
Formula: H
Charge: 1




click to see details on this item[c] + piName: Phosphate
Formula: HO4P
Charge: -2




click to see details on this item[c]
cat-1
Transport
TCE5114Name: Uptake of serotonin
Type: Transport
Location: Cytosol, Extracellular
KEGG ID: NA

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Not applicable
srtnName: Serotonin
Formula: C10H13N2O
Charge: 1




click to see details on this item[e]
srtnName: Serotonin
Formula: C10H13N2O
Charge: 1




click to see details on this item[c]
Not determined
Transport
EX00780Name: Serotonin exchange
Type: Exchange
Location: Extracellular
KEGG ID: NA

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Not applicable
srtnName: Serotonin
Formula: C10H13N2O
Charge: 1




click to see details on this item[e]
Not applicable
Exchange with the environment
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