Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	duri
Name .....................................................	:	Deoxyuridine, etc.2-Deoxyuridine, 2'-Deoxyuridine
Model ID .....................................................	:	C00526
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00526
Formula .....................................................	:	C9H12N2O5
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	duri
Other associations .....................................................	:	See reaction table below (6 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Pyrimidine metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC02099Name: ATP:deoxyuridine 5-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R02099 click to see details on this item	2.7.1.21Name: thymidine kinase Other names: thymidine kinase (phosphorylating), 2'-deoxythymidine kinase, deoxythymidine kinase (phosphorylating) click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + dumpName: dUMP Formula: C9H11N2O8P Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	thk-1	Pyrimidine metabolism
RC02485Name: Deoxycytidine aminohydrolase Type: Regular Location: Cytosol KEGG ID: R02485 click to see details on this item	3.5.4.5Name: cytidine deaminase Other names: cytosine nucleoside deaminase, (deoxy)cytidine deaminase, cdd (gene name), CDA (gene name) click to see details on this item	[c] : dcytName: Deoxycytidine Formula: C9H13N3O4 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	cdd-1 | cdd-2	Pyrimidine metabolism
RC02484Name: deoxyuridine:orthophosphate 2-deoxy-D-ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R02484 click to see details on this item	2.4.2.1Name: purine-nucleoside phosphorylase Other names: inosine phosphorylase, PNPase, PUNPI, PUNPII, inosine-guanosine phosphorylase, nucleotide phosphatase, purine deoxynucleoside phosphorylase, purine deoxyribonucleoside phosphorylase, purine nucleoside phosphorylase, purine ribonucleoside phosphorylase click to see details on this item 2.4.2.3Name: uridine phosphorylase Other names: pyrimidine phosphorylase, UrdPase, UPH, UPase click to see details on this item	[c] : duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item		2dr1pName: 2-Deoxy-D-ribose 1-phosphate Formula: C5H9O7P Charge: -2 click to see details on this item + uraName: Uracil Formula: C4H4N2O2 Charge: 0 click to see details on this item	K02D7.1 | upp-1	Pyrimidine metabolism
RC02102Name: 2-Deoxyuridine 5-monophosphate phosphohydrolase Type: Regular Location: Cytosol KEGG ID: R02102 click to see details on this item	3.1.3.5Name: 5'-nucleotidase Other names: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase click to see details on this item	[c] : dumpName: dUMP Formula: C9H11N2O8P Charge: -2 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	F25B5.3 | Y10G11A.1 | Y71H10B.1	Pyrimidine metabolism
TCE0573Name: Deoxyuridine transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item[e]		duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item[c]	Not determined	Transport
EX00526Name: Deoxyuridine exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	duriName: Deoxyuridine Formula: C9H12N2O5 Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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