Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	gdpfuc
Name .....................................................	:	GDP-L-fucose, etc.GDP-beta-L-fucose
Model ID .....................................................	:	C00325
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00325
Formula .....................................................	:	C16H23N5O15P2
Charge .....................................................	:	-2
Localization .....................................................	:	Cytosol
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	gdpfuc
Other associations .....................................................	:	See reaction table below.
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Fructose and mannose metabolism (c), N-Glycan biosynthesis (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC05692Name: GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing) Type: Regular Location: Cytosol KEGG ID: R05692 click to see details on this item	1.1.1.271Name: GDP-L-fucose synthase Other names: GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase, GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing) click to see details on this item	[c] : gdpddmanName: GDP-4-dehydro-6-deoxy-D-mannose Formula: C16H21N5O15P2 Charge: -2 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced Formula: C21H26N7O17P3 Charge: -4 click to see details on this item		gdpfucName: GDP-L-fucose Formula: C16H23N5O15P2 Charge: -2 click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate Formula: C21H25N7O17P3 Charge: -3 click to see details on this item	ger-1	Fructose and mannose metabolism
RC01951Name: fucose-1-phosphate guanylyltransferase Type: Regular Location: Cytosol KEGG ID: R01951 click to see details on this item	2.7.7.30Name: fucose-1-phosphate guanylyltransferase Other names: GDP fucose pyrophosphorylase, guanosine diphosphate L-fucose pyrophosphorylase, GDP-L-fucose pyrophosphorylase, GDP-fucose pyrophosphorylase, GTP:L-fucose-1-phosphate guanylyltransferase click to see details on this item	[c] : hName: H+ Formula: H Charge: 1 click to see details on this item + fuc1p-LName: L-Fucose 1-phosphate Formula: C6H11O8P Charge: -2 click to see details on this item + gtpName: GTP Formula: C10H12N5O14P3 Charge: -4 click to see details on this item		gdpfucName: GDP-L-fucose Formula: C16H23N5O15P2 Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	K03H1.13	Fructose and mannose metabolism
RC05988Name: glycoprotein 6-alpha-L-fucosyltransferase (acting on n2m2masn) Type: Regular Location: Cytosol KEGG ID: R05988 click to see details on this item	2.4.1.68Name: glycoprotein 6-alpha-L-fucosyltransferase Other names: GDP-fucose---glycoprotein fucosyltransferase, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1->6fucosyltransferase, GDP-L-fucose-glycoprotein fucosyltransferase, glycoprotein fucosyltransferase, guanosine diphosphofucose-glycoprotein fucosyltransferase, GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 6-alpha-L-fucosyltransferase, FucT, GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 6-alpha-L-fucosyltransferase click to see details on this item	[c] : gdpfucName: GDP-L-fucose Formula: C16H23N5O15P2 Charge: -2 click to see details on this item + n2m2masnName: ((N-acetyl-D-glucosaminyl)2-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein) Formula: C50H83N4O35X Charge: 0 click to see details on this item		fn2m2masnName: N4-{N-Acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-[alpha-L-fucosyl-(1,6)]-N-acetyl-beta-D-glucosaminyl}asparagine Formula: C56H93N4O39X Charge: 0 click to see details on this item + gdpName: GDP Formula: C10H12N5O11P2 Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	fut-8	N-Glycan biosynthesis
RC09319Name: glycoprotein 6-alpha-L-fucosyltransferase (acting on nm2masn) Type: Regular Location: Cytosol KEGG ID: R09319 click to see details on this item	2.4.1.68Name: glycoprotein 6-alpha-L-fucosyltransferase Other names: GDP-fucose---glycoprotein fucosyltransferase, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1->6fucosyltransferase, GDP-L-fucose-glycoprotein fucosyltransferase, glycoprotein fucosyltransferase, guanosine diphosphofucose-glycoprotein fucosyltransferase, GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 6-alpha-L-fucosyltransferase, FucT, GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 6-alpha-L-fucosyltransferase click to see details on this item	[c] : gdpfucName: GDP-L-fucose Formula: C16H23N5O15P2 Charge: -2 click to see details on this item + nm2masnName: (N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein) Formula: C42H70N3O30X Charge: 0 click to see details on this item		fnm2masnName: MGnFuc Formula: C48H80N3O34X Charge: 0 click to see details on this item + gdpName: GDP Formula: C10H12N5O11P2 Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	fut-8	N-Glycan biosynthesis

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