WormFlux: mechanistic analysis of C. elegans metabolism

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? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	spmd
Name .....................................................	:	Spermidine, etc.N-(3-Aminopropyl)-1,4-butane-diamine
Model ID .....................................................	:	C00315
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00315
Formula .....................................................	:	C7H22N3
Charge .....................................................	:	+3
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	spmd
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Methionine salvage (c)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01920Name: S-adenosylmethioninamine:putrescine 3-aminopropyltransferase Type: Regular Location: Cytosol KEGG ID: R01920 click to see details on this item	2.5.1.16Name: spermidine synthase Other names: aminopropyltransferase, putrescine aminopropyltransferase, spermidine synthetase, SpeE, S-adenosylmethioninamine:putrescine 3-aminopropyltransferase click to see details on this item	[c] : ametamName: S-Adenosylmethioninamine Formula: C14H24N6O3S Charge: 2 click to see details on this item + ptrcName: Putrescine Formula: C4H14N2 Charge: 2 click to see details on this item		5mtaName: 5-Methylthioadenosine Formula: C11H15N5O3S Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + spmdName: Spermidine Formula: C7H22N3 Charge: 3 click to see details on this item	spds-1	Methionine salvage
RC02869Name: S-adenosylmethioninamine:spermidine 3-aminopropyltransferase Type: Regular Location: Cytosol KEGG ID: R02869 click to see details on this item	2.5.1.16Name: spermidine synthase Other names: aminopropyltransferase, putrescine aminopropyltransferase, spermidine synthetase, SpeE, S-adenosylmethioninamine:putrescine 3-aminopropyltransferase click to see details on this item	[c] : ametamName: S-Adenosylmethioninamine Formula: C14H24N6O3S Charge: 2 click to see details on this item + spmdName: Spermidine Formula: C7H22N3 Charge: 3 click to see details on this item		5mtaName: 5-Methylthioadenosine Formula: C11H15N5O3S Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + sprmName: Spermine Formula: C10H30N4 Charge: 4 click to see details on this item	spds-1	Methionine salvage
DMN0034Name: spermidine demand Type: Demand Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	spmdName: Spermidine Formula: C7H22N3 Charge: 3 click to see details on this item[c]			Not applicable	Demand reactions
TCE5410Name: Spermidine transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	spmdName: Spermidine Formula: C7H22N3 Charge: 3 click to see details on this item[c]		spmdName: Spermidine Formula: C7H22N3 Charge: 3 click to see details on this item[e]	Not determined	Transport
EX00315Name: Spermidine exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	spmdName: Spermidine Formula: C7H22N3 Charge: 3 click to see details on this item[e]			Not applicable	Exchange with the environment

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