WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	ptrc
Name .....................................................	:	Putrescine, etc.1,4-Butanediamine, 1,4-Diaminobutane, Tetramethylenediamine, Butane-1,4-diamine
Model ID .....................................................	:	C00134
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00134
Formula .....................................................	:	C4H14N2
Charge .....................................................	:	+2
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	ptrc
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Arginine metabolism (c), Methionine salvage (c)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00670Name: L-ornithine carboxy-lyase (putrescine-forming) Type: Regular Location: Cytosol KEGG ID: R00670 click to see details on this item	4.1.1.17Name: ornithine decarboxylase Other names: SpeC, L-ornithine carboxy-lyase click to see details on this item	[c] : hName: H+ Formula: H Charge: 1 click to see details on this item + ornName: Ornithine Formula: C5H13N2O2 Charge: 1 click to see details on this item		co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + ptrcName: Putrescine Formula: C4H14N2 Charge: 2 click to see details on this item	F53F10.2 \| odc-1	Arginine metabolism
RC01154Name: acetyl-CoA:putrescine N-acetyltransferase Type: Regular Location: Cytosol KEGG ID: R01154 click to see details on this item	2.3.1.57Name: diamine N-acetyltransferase Other names: spermidine acetyltransferase, putrescine acetyltransferase, putrescine (diamine)-acetylating enzyme, diamine acetyltransferase, spermidine/spermine N1-acetyltransferase, spermidine N1-acetyltransferase, acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase, putrescine acetylase, putrescine N-acetyltransferase click to see details on this item	[c] : accoaName: Acetyl-CoA Formula: C23H34N7O17P3S Charge: -4 click to see details on this item + ptrcName: Putrescine Formula: C4H14N2 Charge: 2 click to see details on this item		coaName: Coenzyme A Formula: C21H32N7O16P3S Charge: -4 click to see details on this item + aprutName: N-Acetylputrescine Formula: C6H15N2O Charge: 1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item	D2023.4	Arginine metabolism
RC01920Name: S-adenosylmethioninamine:putrescine 3-aminopropyltransferase Type: Regular Location: Cytosol KEGG ID: R01920 click to see details on this item	2.5.1.16Name: spermidine synthase Other names: aminopropyltransferase, putrescine aminopropyltransferase, spermidine synthetase, SpeE, S-adenosylmethioninamine:putrescine 3-aminopropyltransferase click to see details on this item	[c] : ametamName: S-Adenosylmethioninamine Formula: C14H24N6O3S Charge: 2 click to see details on this item + ptrcName: Putrescine Formula: C4H14N2 Charge: 2 click to see details on this item		5mtaName: 5-Methylthioadenosine Formula: C11H15N5O3S Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + spmdName: Spermidine Formula: C7H22N3 Charge: 3 click to see details on this item	spds-1	Methionine salvage
TCE5408Name: Putrescine transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	ptrcName: Putrescine Formula: C4H14N2 Charge: 2 click to see details on this item[e]		ptrcName: Putrescine Formula: C4H14N2 Charge: 2 click to see details on this item[c]	Not determined	Transport
EX00134Name: Putrescine exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	ptrcName: Putrescine Formula: C4H14N2 Charge: 2 click to see details on this item[e]			Not applicable	Exchange with the environment

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