WormFlux: mechanistic analysis of C. elegans metabolism

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Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	sprm
Name .....................................................	:	Spermine, etc.N,N'-Bis(3-aminopropyl)-1,4-butanediamine
Model ID .....................................................	:	C00750
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00750
Formula .....................................................	:	C10H30N4
Charge .....................................................	:	+4
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	sprm
Other associations .....................................................	:	See reaction table below.

In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Methionine salvage (c)

iCEL1314

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Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC02869Name: S-adenosylmethioninamine:spermidine 3-aminopropyltransferase Type: Regular Location: Cytosol KEGG ID: R02869 click to see details on this item	2.5.1.16Name: spermidine synthase Other names: aminopropyltransferase, putrescine aminopropyltransferase, spermidine synthetase, SpeE, S-adenosylmethioninamine:putrescine 3-aminopropyltransferase click to see details on this item	[c] : ametamName: S-Adenosylmethioninamine Formula: C14H24N6O3S Charge: 2 click to see details on this item + spmdName: Spermidine Formula: C7H22N3 Charge: 3 click to see details on this item		5mtaName: 5-Methylthioadenosine Formula: C11H15N5O3S Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + sprmName: Spermine Formula: C10H30N4 Charge: 4 click to see details on this item	spds-1	Methionine salvage
DMN0035Name: spermine demand Type: Demand Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	sprmName: Spermine Formula: C10H30N4 Charge: 4 click to see details on this item[c]			Not applicable	Demand reactions
TCE5411Name: Spermine transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	sprmName: Spermine Formula: C10H30N4 Charge: 4 click to see details on this item[e]		sprmName: Spermine Formula: C10H30N4 Charge: 4 click to see details on this item[c]	Not determined	Transport
EX00750Name: Spermine exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	sprmName: Spermine Formula: C10H30N4 Charge: 4 click to see details on this item[e]			Not applicable	Exchange with the environment

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