Network Biomass WormPaths

FBAFlux Balance Analysis PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network

Metabolite Overview

Abbreviation .....................................................	:	hxan
Name .....................................................	:	Hypoxanthine, etc.Purine-6-ol
Model ID .....................................................	:	C00262
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00262
Formula .....................................................	:	C5H4N4O
Charge .....................................................	:	0
Localization .....................................................	:	Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	hxan
Other associations .....................................................	:	See reaction table below (7 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Purine metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC01863Name: inosine:phosphate alpha-D-ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R01863 click to see details on this item	2.4.2.1Name: purine-nucleoside phosphorylase Other names: inosine phosphorylase, PNPase, PUNPI, PUNPII, inosine-guanosine phosphorylase, nucleotide phosphatase, purine deoxynucleoside phosphorylase, purine deoxyribonucleoside phosphorylase, purine nucleoside phosphorylase, purine ribonucleoside phosphorylase click to see details on this item	[c] : insName: Inosine Formula: C10H12N4O5 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item		hxanName: Hypoxanthine Formula: C5H4N4O Charge: 0 click to see details on this item + r1pName: alpha-D-Ribose 1-phosphate Formula: C5H9O8P Charge: -2 click to see details on this item	K02D7.1	Purine metabolism
RC01132Name: IMP:diphosphate phospho-D-ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R01132 click to see details on this item	2.4.2.8Name: hypoxanthine phosphoribosyltransferase Other names: IMP pyrophosphorylase, transphosphoribosidase, hypoxanthine---guanine phosphoribosyltransferase, guanine phosphoribosyltransferase, GPRT, HPRT, guanosine 5'-phosphate pyrophosphorylase, IMP-GMP pyrophosphorylase, HGPRTase, 6-hydroxypurine phosphoribosyltransferase, 6-mercaptopurine phosphoribosyltransferase, GMP pyrophosphorylase, guanine-hypoxanthine phosphoribosyltransferase, guanosine phosphoribosyltransferase, guanylate pyrophosphorylase, guanylic pyrophosphorylase, inosinate pyrophosphorylase, inosine 5'-phosphate pyrophosphorylase, inosinic acid pyrophosphorylase, inosinic pyrophosphorylase, 6-mercaptopurine phosphoribosyltransferase, purine-6-thiol phosphoribosyltransferase click to see details on this item	[c] : hxanName: Hypoxanthine Formula: C5H4N4O Charge: 0 click to see details on this item + prppName: 5-Phospho-alpha-D-ribose 1-diphosphate Formula: C5H8O14P3 Charge: -5 click to see details on this item		impName: IMP Formula: C10H11N4O8P Charge: -2 click to see details on this item + ppiName: Diphosphate Formula: HO7P2 Charge: -3 click to see details on this item	hprt-1	Purine metabolism
RC02748Name: Deoxyinosine:orthophosphate ribosyltransferase Type: Regular Location: Cytosol KEGG ID: R02748 click to see details on this item	2.4.2.1Name: purine-nucleoside phosphorylase Other names: inosine phosphorylase, PNPase, PUNPI, PUNPII, inosine-guanosine phosphorylase, nucleotide phosphatase, purine deoxynucleoside phosphorylase, purine deoxyribonucleoside phosphorylase, purine nucleoside phosphorylase, purine ribonucleoside phosphorylase click to see details on this item	[c] : dinName: Deoxyinosine Formula: C10H12N4O4 Charge: 0 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item		2dr1pName: 2-Deoxy-D-ribose 1-phosphate Formula: C5H9O7P Charge: -2 click to see details on this item + hxanName: Hypoxanthine Formula: C5H4N4O Charge: 0 click to see details on this item	K02D7.1	Purine metabolism
RC01768Name: hypoxanthine:NAD+ oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01768 click to see details on this item	1.17.1.4Name: xanthine dehydrogenase Other names: NAD+-xanthine dehydrogenase, xanthine-NAD+ oxidoreductase, xanthine/NAD+ oxidoreductase, xanthine oxidoreductase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + hxanName: Hypoxanthine Formula: C5H4N4O Charge: 0 click to see details on this item + nadName: Nicotinamide adenine dinucleotide Formula: C21H26N7O14P2 Charge: -1 click to see details on this item		hName: H+ Formula: H Charge: 1 click to see details on this item + nadhName: Nicotinamide adenine dinucleotide - reduced Formula: C21H27N7O14P2 Charge: -2 click to see details on this item + xanName: Xanthine Formula: C5H4N4O2 Charge: 0 click to see details on this item	xdh-1	Purine metabolism
RC01769Name: Hypoxanthine:oxygen oxidoreductase Type: Regular Location: Cytosol KEGG ID: R01769 click to see details on this item	1.17.3.2Name: xanthine oxidase Other names: hypoxanthine oxidase, hypoxanthine:oxygen oxidoreductase, Schardinger enzyme, xanthine oxidoreductase, hypoxanthine-xanthine oxidase, xanthine:O2 oxidoreductase, xanthine:xanthine oxidase click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + hxanName: Hypoxanthine Formula: C5H4N4O Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item		h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + xanName: Xanthine Formula: C5H4N4O2 Charge: 0 click to see details on this item	xdh-1	Purine metabolism
TCE0544Name: Hypoxanthine transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	hxanName: Hypoxanthine Formula: C5H4N4O Charge: 0 click to see details on this item[e]		hxanName: Hypoxanthine Formula: C5H4N4O Charge: 0 click to see details on this item[c]	Not determined	Transport
EX00262Name: Hypoxanthine exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	hxanName: Hypoxanthine Formula: C5H4N4O Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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