Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	ala-B
Name .....................................................	:	beta-Alanine, etc.3-Aminopropionic acid, 3-Aminopropanoate
Model ID .....................................................	:	C00099
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00099
Formula .....................................................	:	C3H7NO2
Charge .....................................................	:	0
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	ala-B
Other associations .....................................................	:	See reaction table below (7 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Aspartate and asparagine metabolism (c,m), Propionate degradation (m), Pyrimidine metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00489Name: L-aspartate 1-carboxy-lyase (beta-alanine-forming) Type: Regular Location: Cytosol KEGG ID: R00489 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[c] : asp-LName: L-Aspartate Formula: C4H6NO4 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	unc-25	Aspartate and asparagine metabolism
RM00489Name: L-aspartate 1-carboxy-lyase (beta-alanine-forming) Type: Regular Location: Mitochondria KEGG ID: R00489 click to see details on this item	4.1.1.15Name: glutamate decarboxylase Other names: L-glutamic acid decarboxylase, L-glutamic decarboxylase, cysteic acid decarboxylase, L-glutamate alpha-decarboxylase, aspartate 1-decarboxylase, aspartic alpha-decarboxylase, L-aspartate-alpha-decarboxylase, gamma-glutamate decarboxylase, L-glutamate 1-carboxy-lyase click to see details on this item	[m] : asp-LName: L-Aspartate Formula: C4H6NO4 Charge: -1 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item		ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item	unc-25	Aspartate and asparagine metabolism
RM00908Name: beta-alanine:2-oxoglutarate aminotransferase Type: Regular Location: Mitochondria KEGG ID: R00908 click to see details on this item	2.6.1.19Name: 4-aminobutyrate---2-oxoglutarate transaminase Other names: beta-alanine-oxoglutarate transaminase, aminobutyrate aminotransferase (ambiguous), beta-alanine aminotransferase, beta-alanine-oxoglutarate aminotransferase, gamma-aminobutyrate aminotransaminase (ambiguous), gamma-aminobutyrate transaminase (ambiguous), gamma-aminobutyrate-alpha-ketoglutarate aminotransferase, gamma-aminobutyrate-alpha-ketoglutarate transaminase, gamma-aminobutyrate:alpha-oxoglutarate aminotransferase, gamma-aminobutyric acid aminotransferase (ambiguous), gamma-aminobutyric acid transaminase (ambiguous), gamma-aminobutyric acid-alpha-ketoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase, gamma-aminobutyric acid-2-oxoglutarate transaminase, gamma-aminobutyric transaminase (ambiguous), 4-aminobutyrate aminotransferase (ambiguous), 4-aminobutyrate-2-ketoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate transaminase, 4-aminobutyric acid 2-ketoglutaric acid aminotransferase, 4-aminobutyric acid aminotransferase (ambiguous), aminobutyrate transaminase (ambiguous), GABA aminotransferase (ambiguous), GABA transaminase (ambiguous), GABA transferase, GABA-alpha-ketoglutarate aminotransferase, GABA-alpha-ketoglutarate transaminase, GABA-alpha-ketoglutaric acid transaminase, GABA-alpha-oxoglutarate aminotransferase, GABA-2-oxoglutarate aminotransferase, GABA-2-oxoglutarate transaminase, GABA-oxoglutarate aminotransferase, GABA-oxoglutarate transaminase, glutamate-succinic semialdehyde transaminase, GabT click to see details on this item	[m] : akgName: 2-Oxoglutarate Formula: C5H4O5 Charge: -2 click to see details on this item + ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item		glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + msaName: Malonate semialdehyde Formula: C3H3O3 Charge: -1 click to see details on this item	gta-1	Propionate degradation
RC00905Name: N-Carbamoyl-beta-alanine amidohydrolase Type: Regular Location: Cytosol KEGG ID: R00905 click to see details on this item	3.5.1.6Name: beta-ureidopropionase click to see details on this item	[c] : calaName: N-Carbamoyl-beta-alanine Formula: C4H7N2O3 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item		ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + co2Name: CO2 Formula: CO2 Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item	upb-1	Pyrimidine metabolism
TCM0192Name: beta-Alanine transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item[c]		ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item[m]	Not determined	Transport
TCE0697Name: beta-Alanine transport Type: Transport Location: Extracellular, Cytosol KEGG ID: NA click to see details on this item	Not applicable	(3.0) ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item[c] + atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item[c] + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item[c]		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item[c] + (3.0) ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item[e] + hName: H+ Formula: H Charge: 1 click to see details on this item[c] + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item[c]	Not determined	Transport
EX00099Name: beta-Alanine exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	ala-BName: beta-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item[e]			Not applicable	Exchange with the environment

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