Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Metabolite Overview

Abbreviation .....................................................	:	pydx5p
Name .....................................................	:	Pyridoxal 5'-phosphate, etc.Pyridoxal phosphate, Pyridoxal 5-phosphate, PLP
Model ID .....................................................	:	C00018
KEGG ID (?) Compounds in KEGG database that match this compound. .....................................................	:	C00018
Formula .....................................................	:	C8H8NO6P
Charge .....................................................	:	-2
Localization .....................................................	:	Mitochondria, Cytosol, Extracellular
BiGG matches (?) Compounds in BiGG database that match this compound. .....................................................	:	pydx5p
Other associations .....................................................	:	See reaction table below (8 reactions in total)
In WormPaths (?) Pathway maps where this metabolite is represented are listed here. Letters after map name indicate the compartments the metabolite is placed in the map: (c) Cytosol (m) Mitochondria (e) Extracellular space .....................................................	:	Alanine metabolism (c), Selenocompound metabolism (c), Vitamin B6 metabolism (c)

iCEL1314

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&). I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme). & indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme). If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC03599Name: L-selenocysteine selenide-lyase (L-alanine-forming) Type: Regular Location: Cytosol KEGG ID: R03599 click to see details on this item	4.4.1.16Name: selenocysteine lyase Other names: selenocysteine reductase, selenocysteine beta-lyase click to see details on this item	[c] : pdx5pName: Pyridoxine 5'-phosphate Formula: C8H10NO6P Charge: -2 click to see details on this item + selcysName: Selenocysteine Formula: C3H7NO2Se Charge: 0 click to see details on this item		ala-LName: L-Alanine Formula: C3H7NO2 Charge: 0 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item + selnName: Selenide Formula: HSe Charge: -1 click to see details on this item	F13H8.9	Alanine metabolism
RC00277Name: Pyridoxamine-5-phosphate:oxygen oxidoreductase (deaminating) Type: Regular Location: Cytosol KEGG ID: R00277 click to see details on this item	1.4.3.5Name: pyridoxal 5'-phosphate synthase Other names: pyridoxamine 5'-phosphate oxidase, pyridoxamine phosphate oxidase, pyridoxine (pyridoxamine)phosphate oxidase, pyridoxine (pyridoxamine) 5'-phosphate oxidase, pyridoxaminephosphate oxidase (EC 1.4.3.5: deaminating), PMP oxidase, pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating) (incorrect), pyridoxamine-phosphate oxidase, PdxH click to see details on this item	[c] : h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + pyam5pName: Pyridoxamine 5'-phosphate Formula: C8H12N2O5P Charge: -1 click to see details on this item		h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item	F57B9.1	Vitamin B6 metabolism
RC00174Name: ATP:pyridoxal 5-phosphotransferase Type: Regular Location: Cytosol KEGG ID: R00174 click to see details on this item	2.7.1.35Name: pyridoxal kinase Other names: pyridoxal kinase (phosphorylating), pyridoxal 5-phosphate-kinase, pyridoxal phosphokinase, pyridoxine kinase click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + pydxName: Pyridoxal Formula: C8H9NO3 Charge: 0 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + hName: H+ Formula: H Charge: 1 click to see details on this item + pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item	pdxk-1	Vitamin B6 metabolism
RC00278Name: Pyridoxine 5-phosphate:oxygen oxidoreductase Type: Regular Location: Cytosol KEGG ID: R00278 click to see details on this item	1.4.3.5Name: pyridoxal 5'-phosphate synthase Other names: pyridoxamine 5'-phosphate oxidase, pyridoxamine phosphate oxidase, pyridoxine (pyridoxamine)phosphate oxidase, pyridoxine (pyridoxamine) 5'-phosphate oxidase, pyridoxaminephosphate oxidase (EC 1.4.3.5: deaminating), PMP oxidase, pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating) (incorrect), pyridoxamine-phosphate oxidase, PdxH click to see details on this item	[c] : o2Name: O2 Formula: O2 Charge: 0 click to see details on this item + pdx5pName: Pyridoxine 5'-phosphate Formula: C8H10NO6P Charge: -2 click to see details on this item		h2o2Name: Hydrogen peroxide Formula: H2O2 Charge: 0 click to see details on this item + pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item	F57B9.1	Vitamin B6 metabolism
DMN0001Name: pyridoxal phosphate demand Type: Demand Location: Cytosol KEGG ID: NA click to see details on this item	Not applicable	pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item[c]			Not applicable	Demand reactions
TCE5323Name: Pyridoxal 5'-phosphate transport Type: Transport Location: Cytosol, Extracellular KEGG ID: NA click to see details on this item	Not applicable	pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item[e]		pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item[c]	Not determined	Transport
TCM0062Name: Pyridoxal 5'-phosphate transport Type: Transport Location: Mitochondria, Cytosol KEGG ID: NA click to see details on this item	Not applicable	pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item[c]		pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item[m]	Not determined	Transport
EX00018Name: Pyridoxal 5'-phosphate exchange Type: Exchange Location: Extracellular KEGG ID: NA click to see details on this item	Not applicable	pydx5pName: Pyridoxal 5'-phosphate Formula: C8H8NO6P Charge: -2 click to see details on this item[e]			Not applicable	Exchange with the environment

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