WormFlux: mechanistic analysis of C. elegans metabolism

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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:

? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
* : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.

Network Biomass WormPaths

PEAPathway Enrichment Analysis

WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal

Enzyme Overview

Enzyme (?) Identification in Enzyme Commission (EC) numbering system. .....................................................	:	6.3.4.2
Name .....................................................	:	CTP synthase (glutamine hydrolysing), etc.UTP---ammonia ligase, Cytidine triphosphate synthetase, Uridine triphosphate aminase, Cytidine 5'-triphosphate synthetase, CTPS (gene name), PyrG (gene name), CTP synthase, UTP:ammonia ligase (ADP-forming)
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. .....................................................	:	K01937E6.3.4.2 pyrG; CTP synthase [EC:6.3.4.2]
Genes .....................................................	:	ctps-1
Localization .....................................................	:	Cytosol
Other associations .....................................................	:	See reaction table below.

External links

Reactions

ID

Enzyme

Reactants

Products

Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses.

Pathway

RC00571Name: UTP:ammonia ligase (ADP-forming) Type: Regular Location: Cytosol KEGG ID: R00571 click to see details on this item	6.3.4.2Name: CTP synthase (glutamine hydrolysing) Other names: UTP---ammonia ligase, cytidine triphosphate synthetase, uridine triphosphate aminase, cytidine 5'-triphosphate synthetase, CTPS (gene name), pyrG (gene name), CTP synthase, UTP:ammonia ligase (ADP-forming) click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + nh4Name: Ammonium Formula: H4N Charge: 1 click to see details on this item + utpName: UTP Formula: C9H11N2O15P3 Charge: -4 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + ctpName: CTP Formula: C9H12N3O14P3 Charge: -4 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	ctps-1	Pyrimidine metabolism
RC00573Name: UTP:L-glutamine amido-ligase (ADP-forming) Type: Regular Location: Cytosol KEGG ID: R00573 click to see details on this item	6.3.4.2Name: CTP synthase (glutamine hydrolysing) Other names: UTP---ammonia ligase, cytidine triphosphate synthetase, uridine triphosphate aminase, cytidine 5'-triphosphate synthetase, CTPS (gene name), pyrG (gene name), CTP synthase, UTP:ammonia ligase (ADP-forming) click to see details on this item	[c] : atpName: ATP Formula: C10H12N5O13P3 Charge: -4 click to see details on this item + gln-LName: L-Glutamine Formula: C5H10N2O3 Charge: 0 click to see details on this item + h2oName: H2O Formula: H2O Charge: 0 click to see details on this item + utpName: UTP Formula: C9H11N2O15P3 Charge: -4 click to see details on this item		adpName: ADP Formula: C10H12N5O10P2 Charge: -3 click to see details on this item + ctpName: CTP Formula: C9H12N3O14P3 Charge: -4 click to see details on this item + glu-LName: L-Glutamate Formula: C5H8NO4 Charge: -1 click to see details on this item + (2) hName: H+ Formula: H Charge: 1 click to see details on this item + piName: Phosphate Formula: HO4P Charge: -2 click to see details on this item	ctps-1	Pyrimidine metabolism

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