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(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
FBAFlux Balance Analysis PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 3.1.4.11
Name ..................................................... : Phosphoinositide phospholipase C, etc.Triphosphoinositide phosphodiesterase, Phosphoinositidase C, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase, Monophosphatidylinositol phosphodiesterase, Phosphatidylinositol phospholipase C, PI-PLC, 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K05860PLCE; phosphatidylinositol phospholipase C epsilon [EC:3.1.4.11], K05857PLCD; phosphatidylinositol phospholipase C delta [EC:3.1.4.11], K01116PLCG1; phosphatidylinositol phospholipase C gamma-1 [EC:3.1.4.11], K05858PLCB; phosphatidylinositol phospholipase C beta [EC:3.1.4.11]
Genes ..................................................... : egl-8, plc-1, plc-2, plc-3, plc-4
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC03435Name: 1-Phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase
Type: Regular
Location: Cytosol
KEGG ID: R03435

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3.1.4.11Name: phosphoinositide phospholipase C
Other names: triphosphoinositide phosphodiesterase, phosphoinositidase C, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase, monophosphatidylinositol phosphodiesterase, phosphatidylinositol phospholipase C, PI-PLC, 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase

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[c] : h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + pail45pName: phosphatidylinositol 4,5-bisphosphate
Formula: C9H14O15P3FULLRCO2FULLR2CO2
Charge: -5




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dag_plName: diacylglycerol (phospholipids)
Formula: C3H6OFULLRCO2FULLR2CO2
Charge: 0




click to see details on this item + hName: H+
Formula: H
Charge: 1




click to see details on this item + mi145pName: "1D-myo-Inositol 1,4,5-trisphosphate"
Formula: C6H9O15P3
Charge: -6




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plc-1 | plc-2 | plc-3 | plc-4 | egl-8
Inositol phosphate metabolism
RC03332Name: phosphatidylinositol phospholipase C
Type: Regular
Location: Cytosol
KEGG ID: R03332

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3.1.4.11Name: phosphoinositide phospholipase C
Other names: triphosphoinositide phosphodiesterase, phosphoinositidase C, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase, monophosphatidylinositol phosphodiesterase, phosphatidylinositol phospholipase C, PI-PLC, 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase

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[c] : h2oName: H2O
Formula: H2O
Charge: 0




click to see details on this item + pailName: Phosphatidylinositol
Formula: C9H16O9PFULLRCO2FULLR2CO2
Charge: -1




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dag_plName: diacylglycerol (phospholipids)
Formula: C3H6OFULLRCO2FULLR2CO2
Charge: 0




click to see details on this item + hName: H+
Formula: H
Charge: 1




click to see details on this item + mi1p-DName: 1D-myo-Inositol 1-phosphate
Formula: C6H11O9P
Charge: -2




click to see details on this item
plc-1 | plc-2 | plc-3 | plc-4 | egl-8
Inositol phosphate metabolism
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