HOME DOWNLOAD CITATION HELP
Umass Logo PSB Logo
(?) Enter a search word or phrase (left box), optionally select an appropriate field (middle), and hit the search button or press enter. This search engine is NOT case sensitive.

Use wild characters " ? " and " * " for efficient search:
  • ? : A single character. E.g., trehalose?phosphatase covers both trehalose phosphatase and trehalose-phosphatase, of which, only the latter fits the nomenclature used in this database.
  • * : Any number of characters. E.g.,tre-* brings all genes from trehalase family; coenzyme*A covers coenzyme A, coenzyme-A, and coenzymeA.
Network Biomass WormPaths
PEAPathway Enrichment Analysis
WormClustClustering- and enrichment-based association of genes with the metabolic network WPSWorm Perturb-Seq portal
Enzyme Overview
Enzyme (?) Identification in Enzyme Commission (EC) numbering system. ..................................................... : 1.3.1.22
Name ..................................................... : 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+), etc.Cholestenone 5alpha-reductase, Testosterone Delta4-5alpha-reductase, Steroid 5alpha-reductase, 3-oxosteroid Delta4-dehydrogenase, 5alpha-reductase, Steroid 5alpha-hydrogenase, 3-oxosteroid 5alpha-reductase, Testosterone Delta4-hydrogenase, 4-ene-3-oxosteroid 5alpha-reductase, Reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase, 4-ene-5alpha-reductase, Delta4-3-ketosteroid 5alpha-oxidoreductase, Cholest-4-en-3-one 5alpha-reductase, Testosterone 5alpha-reductase, 3-oxo-5alpha-steroid 4-dehydrogenase
KO (?) The KEGG orthology group (KO) that is associated with this enzyme. ..................................................... : K12343SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22], K12345SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3.1.94]
Genes ..................................................... : B0024.13, F42F12.3
Localization ..................................................... : Cytosol
Other associations ..................................................... : See reaction table below.
Reactions
ID Enzyme Reactants Products Genes (?) Multiple genes are separated by OR (I) or AND (&).

I indicates that genes are redundant within the group (e.g. paralogs encoding the same enzyme).
& indicates that genes are non-redundant within the group (e.g. genes encoding different subunits of the same enzyme).

If there are multiple groups of genes, as in an enzyme complex with some enzymes associated with multiple genes, or in a case where the same enzyme is associated with different orthology groups with paralogs, each group with multiple genes is shown in parentheses. 		Pathway
RC02497Name: dihydrotestosterone:NADP+ delta4-oxidoreductase
Type: Regular
Location: Cytosol
KEGG ID: R02497

click to see details on this item
1.3.1.22Name: 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
Other names: cholestenone 5alpha-reductase, testosterone Delta4-5alpha-reductase, steroid 5alpha-reductase, 3-oxosteroid Delta4-dehydrogenase, 5alpha-reductase, steroid 5alpha-hydrogenase, 3-oxosteroid 5alpha-reductase, testosterone Delta4-hydrogenase, 4-ene-3-oxosteroid 5alpha-reductase, reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase, 4-ene-5alpha-reductase, Delta4-3-ketosteroid 5alpha-oxidoreductase, cholest-4-en-3-one 5alpha-reductase, testosterone 5alpha-reductase, 3-oxo-5alpha-steroid 4-dehydrogenase

click to see details on this item
[c] : tststeroneName: Testosterone
Formula: C19H28O2
Charge: 0




click to see details on this item + nadphName: Nicotinamide adenine dinucleotide phosphate - reduced
Formula: C21H26N7O17P3
Charge: -4




click to see details on this item + hName: H+
Formula: H
Charge: 1




click to see details on this item
5adtststeroneName: 5alpha-Dihydrotestosterone
Formula: C19H30O2
Charge: 0




click to see details on this item + nadpName: Nicotinamide adenine dinucleotide phosphate
Formula: C21H25N7O17P3
Charge: -3




click to see details on this item
B0024.13 | F42F12.3
Miscellaneous
The information and tools provided in this website are to be used for academic purposes only.